Evidence map›Paper›PMID 33635729›Full record

ReviewThe British journal of radiology2021

Quantitative magnetic resonance imaging for chronic liver disease.

Guilherme Moura Cunha, Patrick J Navin, Kathryn J Fowler, Sudhakar K Venkatesh, Richard L Ehman, Claude B Sirlin

Abstract readReview
In one paragraph

Review in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Abdominal simultaneous 3D water TMagnetic resonance in medicine · 2026
    Article
  7. Article
  8. Free-breathing, fat-corrected TMagnetic resonance in medicine · 2024
    Article
  9. Radiology of fibrosis part II: abdominal organs.Journal of translational medicine · 2024
    Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Guilherme Moura CunhaDepartment of Radiology, Liver Imaging Group, University of California San Diego, San Diego, CA, USA.ORCID https://orcid.org/0000-0001-6403-5155
Patrick J NavinDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Kathryn J FowlerDepartment of Radiology, Liver Imaging Group, University of California San Diego, San Diego, CA, USA.
Sudhakar K VenkateshDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Richard L EhmanDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Claude B SirlinDepartment of Radiology, Liver Imaging Group, University of California San Diego, San Diego, CA, USA.

Funding

Magnetic Resonance ElastographyR37EB001981 · NIBIB · MAYO CLINIC ROCHESTER · PI EHMAN, RICHARD L. · 2016 to 2025
$4.0M
NIBIB NIH HHS R37 EB001981
6 · The paper itself

Abstract

Chronic liver disease (CLD) has rapidly increased in prevalence over the past two decades, resulting in significant morbidity and mortality worldwide. Historically, the clinical gold standard for diagnosis, assessment of severity, and longitudinal monitoring of CLD has been liver biopsy with histological analysis, but this approach has limitations that may make it suboptimal for clinical and research settings. Magnetic resonance (MR)-based biomarkers can overcome the limitations by allowing accurate, precise, and quantitative assessment of key components of CLD without the risk of invasive procedures. This review briefly describes the limitations associated with liver biopsy and the need for non-invasive biomarkers. It then discusses the current state-of-the-art for MRI-based biomarkers of liver iron, fat, and fibrosis, and inflammation.

Indexed as

BiomarkersBiopsyChronic DiseaseElasticity Imaging TechniquesFatty LiverHepatitisHumansIronLiverLiver CirrhosisLiver DiseasesMagnetic Resonance ImagingNon-alcoholic Fatty Liver DiseaseBiomarkersIron

Identifiers

PMID33635729
PMCPMC8506189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.