Evidence map›Paper›PMID 33635417›Full record

ReviewCellular and molecular neurobiology2022

New Insights into Stroke Prevention and Treatment: Gut Microbiome.

Linna Zhao, Liji Yang, Yuying Guo, Jie Xiao, Junping Zhang, Shixin Xu

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Emerging Stroke Risk Factors: A Focus on Infectious and Environmental Determinants.Journal of cardiovascular development and disease · 2024
    Review
  7. Article
  8. Acupuncture influences multiple diseases by regulating gut microbiota.Frontiers in cellular and infection microbiology · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Introduction to the Special Issue "The Brain-Gut Axis".Cellular and molecular neurobiology · 2022
    Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Linna Zhao *First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.ORCID http://orcid.org/0000-0003-3918-6722
Liji Yang *First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
Yuying GuoFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
Jie XiaoFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
Junping ZhangFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
Shixin XuFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. shixinxu1973@outlook.com.
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine · CNTianjin University of Traditional Chinese Medicine · CNTianjin Institute of Pharmaceutical Research (China) · CN

Funding

Natural Science Foundation of Tianjin Municipal Science and Technology Commission 19JCZDJC37100the National Natural Science Foundation of China 81774059
6 · The paper itself

Abstract

Stroke, a lethal neurological disease, accounts for a grave economic burden on society. Despite extensive basic and clinical studies on stroke prevention, a precise effective treatment approach for stroke at this stage remains unavailable. The majority of our body's gut microbiota plays a vital role in food digestion, immune regulation, and nervous system development, which is highly associated with the development of some diseases. Multiple clinical studies have documented variation in the composition of gut microbiota between stroke patients and healthy counterparts. Moreover, the intervention of intestinal symbiotic microorganisms via several mechanisms plays an active role in stroke prognosis. In the prevention and treatment of stroke, the gut microbiota gives off a seductive glow, this is a promising therapeutic target. This paper summarizes the current knowledge of stroke and gut microbiota, and systematically describes the possible mechanisms of interaction between stroke and gut microbiota, the relationship between stroke-related risk factors and gut microbiota, and the treatment of gut flora using microorganisms. Thus, it could valuably elucidate the correlation of gut microbiota with stroke incidence, providing stroke researchers with a new strategy for stroke prevention and treatment by regulating gut microbiota.

Indexed as

Gastrointestinal MicrobiomeNervous System DiseasesStrokeHumansRisk FactorsGut microbiotaMicrobiota-gut-brain axisStrokeStroke risk factors

Identifiers

PMID33635417
PMCPMC11441219
OpenAlexW3130770251

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.