Evidence map›Paper›PMID 33635385›Full record

Trial reportPsychopharmacology2021

The acute effects of alcohol on state rumination in the laboratory.

O Merve Mollaahmetoglu, Edward Palmer, Emily Maschauer, Melissa C Nolan, Tobias Stevens, Molly Carlyle, Lorna Hardy, Edward R Watkins, Celia J A Morgan

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

O Merve MollaahmetogluPsychopharmacology and Addiction Research Centre (PARC), University of Exeter, Washington Singer Building, Perry Road, Exeter, EX4 4QG, UK. om301@exeter.ac.uk.ORCID http://orcid.org/0000-0002-3386-197X
Edward PalmerPsychopharmacology and Addiction Research Centre (PARC), University of Exeter, Washington Singer Building, Perry Road, Exeter, EX4 4QG, UK.
Emily MaschauerPsychopharmacology and Addiction Research Centre (PARC), University of Exeter, Washington Singer Building, Perry Road, Exeter, EX4 4QG, UK.
Melissa C NolanPsychopharmacology and Addiction Research Centre (PARC), University of Exeter, Washington Singer Building, Perry Road, Exeter, EX4 4QG, UK.
Tobias StevensPsychopharmacology and Addiction Research Centre (PARC), University of Exeter, Washington Singer Building, Perry Road, Exeter, EX4 4QG, UK.
Molly CarlyleSchool of Psychology, University of Queensland, St. Lucia, QLD, Australia.
Lorna HardyPsychopharmacology and Addiction Research Centre (PARC), University of Exeter, Washington Singer Building, Perry Road, Exeter, EX4 4QG, UK.
Edward R WatkinsSMART Lab, University of Exeter, Washington Singer Building, Perry Road, Exeter, EX4 4QG, UK.
Celia J A MorganPsychopharmacology and Addiction Research Centre (PARC), University of Exeter, Washington Singer Building, Perry Road, Exeter, EX4 4QG, UK.
University of Exeter · GBThe University of Queensland · AU

Funding

Medical Research Council MR/L023032/1
6 · The paper itself

Abstract

rationaleRumination is a repetitive, negative, self-focused thinking style associated with various forms of psychopathology. Recent studies suggest that rumination increases craving for alcohol and predicts harmful drinking and alcohol-related problems. However, the acute effects of alcohol on rumination have not been previously studied. It is proposed that alcohol may reduce ruminative thinking through decreasing negative mood.

objectivesIn the present study, we aimed to test the previously unexplored effects of acute alcohol consumption on rumination in a hazardous drinking population.

methodsWe conducted a randomised placebo-controlled laboratory study to examine the effect of low (0.4 g kg

resultsWe found a significant decrease in state rumination in the low-dose alcohol group compared to placebo at 30 min post-alcohol consumption, but no difference was observed between the high-dose alcohol and placebo groups. Mediation analysis provided evidence for an indirect effect of alcohol on state rumination through concurrent changes in negative mood.

conclusionsThese findings suggest that acute alcohol consumption can regulate negative mood and concurrently rumination, providing preliminary evidence for the role of rumination in alcohol use disorders. Rumination may be a treatment target in alcohol use disorders.

Indexed as

AdolescentAdultAffectAlcohol DrinkingAlcoholismAlcohol-Related DisordersChildCognitionDouble-Blind MethodFemaleHumansLaboratoriesMalePilot ProjectsYoung AdultAlcohol use disordersDepressionNegative affectRumination

Identifiers

PMID33635385
PMCPMC8139935
OpenAlexW3133201949

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.