Evidence map›Paper›PMID 33635163›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2021

Role of t-tubule remodeling on mechanisms of abnormal calcium release during heart failure development in canine ventricle.

Sean Yamakawa, Daniel Wu, Mona Dasgupta, Havisha Pedamallu, Binita Gupta, Rishi Modi, Maryam Mufti, Caitlin O'Callaghan, Michael Frisk, William E Louch and 11 more

Open access · greenAbstract readVideo-Audio Media
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Proteolytic degradation of atrial sarcomere proteins underlies contractile defects in atrial fibrillation.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 2 countries.

Sean YamakawaFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Daniel WuFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Mona DasguptaFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Havisha PedamalluFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Binita GuptaFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Rishi ModiFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Maryam MuftiFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Caitlin O'CallaghanInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Michael FriskInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
William E LouchFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Rishi AroraCalifornia State University Northridge, Los Angeles, California.
Yohannes ShiferawFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Amy BurrellFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Juliet RyanFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Lauren NelsonFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Madeleine ChowFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Sanjiv J ShahThe Masonic Medical Research Institute, Utica, New York.
Gary AistrupFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Junlan ZhouFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
William MarszalecFeinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0002-5655-8201
J Andrew Wasserstrom
Northwestern University · USOslo University Hospital · NOCalifornia State University, Northridge · USMasonic Medical Research Laboratory · US

Funding

Transition from Risk Factors to Early HF: Prevalence, Pathogenesis, and PhenomicsR01HL127028 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BERTONI, ALAIN GERALD, SHAH, SANJIV J · 2015 to 2018
$6.5M
Study of Cardiac Mechanics in Systemic HypertensionR01HL107577 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SHAH, SANJIV J · 2011 to 2019
$4.1M
Atrial arrhythmias and Ca2+ waves in HF: simulation and experimental studiesR01HL119095 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SHIFERAW, YOHANNES, WASSERSTROM, JOHN ANDREW · 2014 to 2018
$3.0M
Machine learning for the automated identification and tracking of rare myocardial diseasesR01HL140731 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MACRAE, CALUM A., SHAH, SANJIV J · 2018 to 2021
$2.8M
Pathophysiological Significance of Atrial Fibrillation Electrogram PatternsR01HL125881 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARORA, RISHI · 2015 to 2019
$2.4M
Oxidative stress contributes to atrial fibrillation by causing remodeling of the autonomic nervous systemR01HL140061 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARORA, RISHI · 2018 to 2021
$2.3M
Precision Medicine for Dilated Cardiomyopathy—Novel Assessment of Cardiac Mechanics via Speckle Tracking Echocardiography to Identify Early PhenotypesR01HL149423 · NHLBI · OHIO STATE UNIVERSITY · PI HERSHBERGER, RAY E., KINNAMON, DANIEL DAVIS · 2019 to 2022
$1.6M
NHLBI NIH HHS R01 HL107577NHLBI NIH HHS R01 HL119095NHLBI NIH HHS R01 HL125881NHLBI NIH HHS R01 HL127028NHLBI NIH HHS R01 HL140061NHLBI NIH HHS R01 HL140731NHLBI NIH HHS R01 HL149423
6 · The paper itself

Abstract

The goal of this work was to investigate the role of t-tubule (TT) remodeling in abnormal Ca

Indexed as

Calcium SignalingAnimalsArrhythmias, CardiacCalciumCardiac Pacing, ArtificialDisease Models, AnimalDogsFemaleHeart FailureMaleMyocytes, CardiacVentricular Function, LeftVentricular Function, RightVentricular PressureCalciumcalciumcalcium wavesheart failuretransverse tubuleventricle

Identifiers

PMID33635163
PMCPMC8260383
OpenAlexW3132306037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.