Evidence map›Paper›PMID 33634890›Full record

Observational studyVox sanguinis2021

Transfusion profile, clinical characteristics, comorbidities and outcomes of 3014 hospitalized patients diagnosed with COVID-19 in Brazil.

Leandro Felipe Figueiredo Dalmazzo, Alyne Ferreira de Almendra Freitas, Brunna Eulálio Alves, Diogo Kloppel Cardoso, Eduardo Ferro de Carvalho, Fabiana Akil, Fernanda da Cunha Vieira Perini, Karina Todeschini Pires, Ludmila Coutinho de Aguiar, Mara Cabral Moraes and 7 more

Abstract readObservational Study
In one paragraph

Observational study in Vox sanguinis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Leandro Felipe Figueiredo DalmazzoGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.ORCID https://orcid.org/0000-0002-9617-582X
Alyne Ferreira de Almendra FreitasGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Brunna Eulálio AlvesGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Diogo Kloppel CardosoGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Eduardo Ferro de CarvalhoGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Fabiana AkilGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Fernanda da Cunha Vieira PeriniGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Karina Todeschini PiresGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Ludmila Coutinho de AguiarGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Mara Cabral MoraesGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Maria Isabel Ayrosa MadeiraGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Pablo Raphael Gomiero AlvesGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Ruth Helena Perdiz WatanabeGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Silvia Helena da Silva Sá TeixeiraGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Tatiana Covas PereiraGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Viviani de Lourdes Rosa PessoaGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.
Sérgio Domingos VieiraGrupo Gestor de Serviços de Hemoterapia - Grupo GSH, Sao Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe novel coronavirus disease-2019 (COVID-19) caused a sudden and unexpected increase in the number of hospital admissions and deaths worldwide. The impact of social distancing on blood stocks was significant. Data on the use of blood products by patients with COVID-19 are scarce. MATERIAL AND

methodsA retrospective observational study was conducted by analysing the medical records of 3014 hospitalized COVID-19 patients in 16 Brazilian hospitals. Individual data related to clinical, laboratory and transfusion characteristics and outcomes of these patients were collected. Patients characteristics association with mortality and transfusion need were tested independently by logistic regression models.

resultsPatients mean age was 57·6 years. In 2298 (76·2%) patients, there was an underlying clinical comorbidity. A total of 1657 (55%) patients required admission to intensive care unit (ICU), and 943 (31%) patients required ventilatory support and orotracheal intubation (OTI). There was a total of 471 (15·6%) deaths among all patients. 325 patients (10·7%) required blood transfusion; 3187 blood products were transfused: 1364 red blood cells in 303 patients, 1092 platelet units in 78 patients, 303 fresh frozen plasma in 49 patients and 423 cryoprecipitates in 21 patients. The mortality among patients who received transfusion was substantially higher than that among the total study population.

conclusionNeed for transfusion was low in COVID-19 patients, but significantly higher in patients admitted to ICU and in those who needed OTI. Knowledge of the transfusion profile of these patients allows better strategies for maintaining the blood stocks of hospitals during the pandemic.

Indexed as

COVID-19Blood TransfusionBrazilComorbidityHospitalizationHumansInfant, NewbornIntensive Care UnitsRespiration, ArtificialRetrospective StudiesSARS-CoV-2COVID-19mortalitySARSSARS-COV-2transfusion

Identifiers

PMID33634890
PMCPMC8014314

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.