Evidence map›Paper›PMID 33634831›Full record

Trial reportJournal of rehabilitation medicine2021

Explore combined use of transcranial direct current stimulation and cognitive training on executive function after stroke.

Yuan-Wen Liu, Zhong-Hua Chen, Jing Luo, Ming-Yu Yin, Li-Li Li, Yu-De Yang, Hai-Qing Zheng, Zhen-Hong Liang, Xi-Quan Hu

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of rehabilitation medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05814588 (Effects of Anodal Transcranial Direct Current Stimulation on Cognition in Subacute Stroke), which is not on this map. Cited by 18 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05814588 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Anodal Transcranial Direct Current Stimulation on Cognition in Subacute Stroke

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2023Enrolled56ConditionsStrokeArmsAnodal TDCS, Sham Anodal TDCS
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Trial
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  16. Reversing the Ruin: Rehabilitation, Recovery, and Restoration After Stroke.Current neurology and neuroscience reports · 2022
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuan-Wen LiuRehabilitation Medicine, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Zhong-Hua Chen
Jing Luo
Ming-Yu Yin
Li-Li Li
Yu-De Yang
Hai-Qing Zheng
Zhen-Hong Liang
Xi-Quan Hu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the effects of transcranial direct current stimulation combined with cognitive training on executive function and activities of daily living performance among stroke patients.

methodsA total of 50 subjects were enrolled and randomly allocated into 2 groups of 25 each. The real-transcranial direct current stimulation group was simultaneously subjected to transcranial direct current stimulation and cognitive training, while the sham-transcranial direct current stimulation group was simultaneously subjected to sham transcranial direct current stimulation and cognitive training. At baseline, and after treatment, each subject was assessed with the Wisconsin Card Sorting Test (WCST), Stroop Color-Word Test (SCWT), Digital Symbol Test (DST), Mini-mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA) and Activities of Daily Living Scale (ADLs).

resultsAfter treatment, the gains in most indices of WCST, SCWT, DST, MMSE, MoCA and ADLs in the real-transcranial direct current stimulation group were significantly higher than those in the sham-transcranial direct current stimulation group (p<0.05). Nonetheless, no significant differences were noted in the gains in SCWT (including only Part A time and error, and Part B time) and activities of daily living (including only basic activities of daily living) between the 2 groups (p>>0.05).

conclusionTranscranial direct current stimulation combined with cognitive training was found to significantly enhance executive function and instrumental activities of daily living performance among stroke patients.

Indexed as

AdolescentAdultAgedCognitive Behavioral TherapyExecutive FunctionFemaleHumansMaleMiddle AgedStrokeStroke RehabilitationTranscranial Direct Current StimulationYoung Adultactivities of daily livingcognitive trainingexecutive functionstroketranscranial direct current stimulation

Identifiers

PMID33634831
PMCPMC8814854

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.