Evidence map›Paper›PMID 33634708›Full record

ArticleJournal of the American Heart Association2021

Blood Biomarker Panels for the Early Prediction of Stroke-Associated Complications.

Júlia Faura, Alejandro Bustamante, Silvia Reverté, Teresa García-Berrocoso, Mónica Millán, Mar Castellanos, Blanca Lara-Rodríguez, Josep Zaragoza, Oriol Ventura, María Hernández-Pérez and 8 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Júlia FauraNeurovascular Research Laboratory Vall d'Hebron Institute of Research (VHIR)Universitat Autònoma de Barcelona Barcelona Spain.
Alejandro BustamanteNeurovascular Research Laboratory Vall d'Hebron Institute of Research (VHIR)Universitat Autònoma de Barcelona Barcelona Spain.
Silvia RevertéStroke Unit Hospital Universitari Verge de la Cinta de Tortosa Tortosa Spain.
Teresa García-BerrocosoNeurovascular Research Laboratory Vall d'Hebron Institute of Research (VHIR)Universitat Autònoma de Barcelona Barcelona Spain.
Mónica MillánStroke Unit Hospital Universitari Germans Trias i Pujol Barcelona Spain.
Mar CastellanosDepartment of Neurology Complejo Hospitalario Universitario A Coruña, A Coruña Biomedical Research Institute Spain.
Blanca Lara-RodríguezStroke Unit Hospital Universitari de Bellvitge Barcelona Spain.
Josep ZaragozaStroke Unit Hospital Universitari Verge de la Cinta de Tortosa Tortosa Spain.
Oriol VenturaNeurovascular Research Laboratory Vall d'Hebron Institute of Research (VHIR)Universitat Autònoma de Barcelona Barcelona Spain.
María Hernández-PérezStroke Unit Hospital Universitari Germans Trias i Pujol Barcelona Spain.
Cecile van EendenburgStroke Unit Hospital Universitari Josep Trueta Girona Spain.
Pere CardonaStroke Unit Hospital Universitari de Bellvitge Barcelona Spain.
Elena López-CancioStroke Unit Hospital Universitario Central de Asturias Oviedo Spain.
David CánovasDepartment of Neurology Hospital Universitari Parc Taulí Sabadell Spain.
Joaquín SerenaStroke Unit Hospital Universitari Josep Trueta Girona Spain.
Marta RubieraStroke, Unit, Department of Neurology Hospital Universitari Vall d'Hebron Barcelona Spain.
Antoni DávalosStroke Unit Hospital Universitari Germans Trias i Pujol Barcelona Spain.
Joan MontanerNeurovascular Research Laboratory Vall d'Hebron Institute of Research (VHIR)Universitat Autònoma de Barcelona Barcelona Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Acute decompensated heart failure (ADHF) and respiratory tract infections (RTIs) are potentially life-threatening complications in patients experiencing stroke during hospitalization. We aimed to test whether blood biomarker panels might predict these complications early after admission. Methods and Results Nine hundred thirty-eight patients experiencing ischemic stroke were prospectively recruited in the Stroke-Chip study. Post-stroke complications during hospitalization were retrospectively evaluated. Blood samples were drawn within 6 hours after stroke onset, and 14 biomarkers were analyzed by immunoassays. Biomarker values were normalized using log-transformation and

Indexed as

Early DiagnosisAgedAged, 80 and overBiomarkersBrain IschemiaFemaleFibrin Fibrinogen Degradation ProductsFollow-Up StudiesHeart FailureHumansMaleNatriuretic Peptide, BrainPeptide FragmentsPredictive Value of TestsProspective StudiesProtein PrecursorsBiomarkersFibrin Fibrinogen Degradation Productsfibrin fragment DNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)Protein PrecursorsADHFbiomarkersstrokestroke‐associated infection

Identifiers

PMID33634708
PMCPMC8174272

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.