Evidence map›Paper›PMID 33634704›Full record

Observational studyJournal of the American Heart Association2021

Adverse Outcomes Associated With Higher Mean Blood Pressure and Greater Blood Pressure Variability Immediately After Successful Embolectomy in Those With Acute Ischemic Stroke, and the Influence of Pretreatment Collateral Circulation Status.

Dacheng Liu, Ximing Nie, Yuesong Pan, Hongyi Yan, Yuehua Pu, Yufei Wei, Yuan Cai, Yarong Ding, Qixuan Lu, Zhe Zhang and 13 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  4. Unfavorable clinical outcomes in patients with good collateral scores following endovascular treatment for acute ischemic stroke of the anterior circulation: The UNCLOSE study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 4 institutions in 3 countries.

Dacheng LiuDepartment of Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Ximing NieDepartment of Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Yuesong PanDepartment of Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Hongyi YanChina National Clinical Research Center for Neurological Diseases Beijing China.
Yuehua PuDepartment of Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Yufei WeiDepartment of Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Yuan CaiDepartment of Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Yarong DingDepartment of Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Qixuan LuDepartment of Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Zhe ZhangDepartment of Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Weibin GuDepartment of Radiology Beijing Tiantan HospitalCapital Medical University Beijing China.
Xinyi HouDepartment of Radiology Beijing Tiantan HospitalCapital Medical University Beijing China.
Zhonghua YangDepartment of Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Miao WenDepartment of Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Penglian WangDepartment of Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Gaoting MaDepartment of Interventional Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Ning MaDepartment of Interventional Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Zhongrong MiaoDepartment of Interventional Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Xinyi LengDepartment of Medicine and Therapeutics, Prince of Wales Hospital Chinese University of Hong Kong Hong Kong SAR China.
Bernard YanDepartment of Medicine and Neurology Melbourne Brain Centre at the Royal Melbourne HospitalUniversity of Melbourne Parkville Victoria Australia.
Stephen M DavisDepartment of Medicine and Neurology Melbourne Brain Centre at the Royal Melbourne HospitalUniversity of Melbourne Parkville Victoria Australia.
Yongjun WangDepartment of Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Liping LiuDepartment of Neurology Beijing Tiantan HospitalCapital Medical University Beijing China.
Capital Medical University · CNThe Royal Melbourne Hospital · AUChinese University of Hong Kong · HKNational Clinical Research Center for Digestive Diseases · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background To investigate whether collateral status could modify the associations between post-thrombectomy blood pressure (BP) measures and outcomes. Methods and Results Patients with anterior-circulation large-vessel-occlusion successfully recanalized in a multicenter endovascular thrombectomy registry were enrolled. Pretreatment collateral status was graded and dichotomized (good/poor) in angiography. Maximum, minimum, and mean systolic BP (SBP) and BP variability (assessed by the SD, coefficient of variation) during the initial 24 hours after endovascular thrombectomy were obtained. The primary outcome was unfavorable 90-day outcome (modified Rankin Scale score 3-6). Secondary outcomes included symptomatic intracranial hemorrhage and 90-day mortality. Adjusted odds ratios (aOR) of BP parameters over the outcomes were obtained in all patients and in patients with good/poor collaterals. Among 596 patients (mean age 66 years; 59.9% males), 302 (50.7%) patients had unfavorable 90-day outcome. In multivariable analyses, higher mean SBP (aOR, 1.59 per 10 mm Hg increment; 95% CI, 1.26-2.02;

Indexed as

RegistriesAcute DiseaseAgedBlood PressureCerebral AngiographyCollateral CirculationEmbolectomyEndovascular ProceduresFemaleFollow-Up StudiesHumansHypertensionIschemic StrokeMalePreoperative PeriodProspective Studiesblood pressureblood pressure variabilitycollateralendovascular treatmentoutcome

Identifiers

PMID33634704
PMCPMC8174261
OpenAlexW3132284133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.