Evidence map›Paper›PMID 33634606›Full record

ArticleESC heart failure2021

Acute heart transplantation from mechanical circulatory support in a human immunodeficiency virus-positive patient with fulminant myocarditis.

Zsofia Szakal-Toth, Janos Szlavik, Adam Soltesz, Viktor Berzsenyi, Gergely Csikos, Tamas Varga, Kristof Racz, Akos Kiraly, Balazs Sax, Istvan Hartyanszky and 5 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Zsofia Szakal-TothHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Janos SzlavikNational Institute for Infectology and Haematology, South-Pest Hospital Centre, Budapest, Hungary.
Adam SolteszDepartment of Anaesthesiology and Intensive Therapy, Semmelweis University, Budapest, Hungary.
Viktor BerzsenyiDepartment of Anaesthesiology and Intensive Therapy, Semmelweis University, Budapest, Hungary.
Gergely CsikosDepartment of Anaesthesiology and Intensive Therapy, Semmelweis University, Budapest, Hungary.
Tamas VargaDepartment of Anaesthesiology and Intensive Therapy, Semmelweis University, Budapest, Hungary.
Kristof RaczDepartment of Anaesthesiology and Intensive Therapy, Semmelweis University, Budapest, Hungary.
Akos KiralyHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Balazs SaxHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Istvan HartyanszkyHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Attila Fintha1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary.
Zoltan ProhaszkaDepartment of Medicine and Haematology, Semmelweis University, Budapest, Hungary.
Katalin MonostoryInstitute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.
Bela MerkelyHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Endre NemethDepartment of Anaesthesiology and Intensive Therapy, Semmelweis University, Budapest, Hungary.ORCID 0000-0001-6033-4297
Semmelweis University · HUInstitute of Molecular Life Sciences · HUNational Center for Epidemiology · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the establishment of highly active antiretroviral therapy, survival rates have improved among patients with human immunodeficiency virus infection giving them the possibility to become transplant candidates. Recent publications revealed that human immunodeficiency virus-positive heart transplant recipients' survival is similar to non-infected patients. We present the case of a 40-year-old human immunodeficiency virus infected patient, who was hospitalized due to severely decreased left ventricular function with a possible aetiology of acute myocarditis, that has later been confirmed by histological investigation of myocardial biopsy. Due to rapid progression to refractory cardiogenic shock, extracorporeal membrane oxygenation implantation had been initiated, which was upgraded to biventricular assist device later. On the 35th day of upgraded support, the patient underwent heart transplantation uneventfully. Our clinical experience confirms that implementation of temporary mechanical circulatory support and subsequent cardiac transplantation might be successful in human immunodeficiency virus-positive patients even in case of new onset, irreversible acute heart failure.

Indexed as

Heart-Assist DevicesHeart TransplantationMyocarditisAdultHIVHumansShock, CardiogenicAcute heart failureAcute myocarditisHeart transplantationHuman immunodeficiency virusMechanical circulatory supportSecondary thrombotic microangiopathy

Identifiers

PMID33634606
PMCPMC8006693
OpenAlexW3129657430

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.