ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2021
Dementia in Latin America: Paving the way toward a regional action plan.
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Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 10 of them syntheses that pooled it.
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88citing papers in PubMed, 10 pooled it
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Who cites it
88 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Factors linked to informal caregiver burden in dementia across Latin America and the Caribbean: A systematic review and meta-analysis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Pooled it
- Risk factors for HIV-associated neurocognitive impairment and frailty in aging people with HIV in Latin America: a systematic review.BMC neurology · 2026Pooled it
- Association of apolipoprotein E variants on Alzheimer's disease in Latin America: A systematic review and meta-analysis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Pooled it
- Structural Brain Differences in the Alzheimer's Disease Continuum: Insights Into the Heterogeneity From a Large Multisite Neuroimaging Consortium.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Pooled it
- Healthy aging meta-analyses and scoping review of risk factors across Latin America reveal large heterogeneity and weak predictive models.Nature aging · 2024Pooled it
- The first genome-wide association study in the Argentinian and Chilean populations identifies shared genetics with Europeans in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Pooled it
- Systematic review: fluid biomarkers and machine learning methods to improve the diagnosis from mild cognitive impairment to Alzheimer's disease.Alzheimer's research & therapy · 2023Pooled it
- Prevalence of dementia in Latin America and Caribbean countries: Systematic review and meta-analyses exploring age, sex, rurality, and education as possible determinants.Ageing research reviews · 2022Pooled it
- The prevalence of mild cognitive impairment in Latin America and the Caribbean: a systematic review and meta-analysis.Aging & mental health · 2022Pooled it
- Systematic Review: Genetic, Neuroimaging, and Fluids Biomarkers for Frontotemporal Dementia Across Latin America Countries.Frontiers in neurology · 2021Pooled it
- Generalizability of EEG-Based DEMENTIA Classifiers: A Multicenter study of Alzheimer's, MCI, and FTD.medRxiv : the preprint server for health sciences · 2026Article
- Dementia in the Middle East and North Africa: an integrative narrative review of epidemiology, risk structure, and health system implications.Journal of global health · 2026Review
- Emerging directions in tauopathy research.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Recommendations for genetic counseling for individuals at risk of autosomal dominant Alzheimer's disease in Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Normative cognitive data and psychometric validation of the 10/66 harmonized assessment protocol in Latin American.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- The landscape of dementia research, diagnosis, treatment, and care in Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Scientific knowledge about dementia: From the Global South to the world.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Towards a Latin American neuropsychiatry: challenges and opportunities.Lancet regional health. Americas · 2026Review
- Article
- A feasibility pilot study on the effects of a combined cognitive and physical intervention program in older adults in Panama.Frontiers in dementia · 2026Article
28 more citing papers are in PubMed but not listed here.
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Authors and funding
102 authors.
Mario Alfredo ParraSchool of Psychological Sciences and Health, Graham Hills Building, Glasgow, G1 1QE, UK, Universidad Autónoma del Caribe, Programa de Psicología, University of Strathclyde, Barranquilla, Colombia.
Sandra BaezUniversidad de los Andes, Bogotá, Colombia.
Lucas SedeñoConsejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Buenos Aires, Argentina.
Cecilia Gonzalez CampoCognitive Neuroscience Center (CNC), Universidad de San Andres, Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Buenos Aires, Argentina.
Hernando Santamaría-GarcíaPontificia Universidad Javeriana, Medical School, Physiology and Psychiatry Departments, Memory and Cognition Center Intellectus, Hospital Universitario San Ignacio, Bogotá, Colombia.
Ivan AprahamianDepartment of Internal Medicine, Faculty of Medicine of Jundiaí, Group of Investigation on Multimorbidity and Mental Health in Aging (GIMMA), Jundiaí, State of São Paulo, Brazil.
Paulo Hf BertolucciDepartment of Neurology and Neurosurgery, Escola Paulista de Medicina, Federal University of São Paulo - UNIFESP, São Paulo, Brazil.
Julian BustinINECO Foundation, Institute of Cognitive and Translational Neuroscience (INCYT), Favaloro University, Buenos Aires, Argentina.
Maria Aparecida Camargos BicalhoDepartment of Clinical Medicine, Federal University of Minas Gerais, Brazil.
Carlos Cano-GutierrezMedical School, Geriatric Unit, Memory and Cognition Center-Intellectus, Aging Institute, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, Bogotá, Colombia.
Paulo CaramelliFaculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Marcia L F ChavesNeurology Service, Hospital de Clínicas de Porto Alegre e Universidade Federal do Rio Grande do Sul, Brazil.
Patricia CogramLaboratory of Molecular Neuropsychiatry, INECO Foundation, National Scientific and Technical Research Council, Institute of Cognitive and Translational Neuroscience (INCyT), Favaloro University, Buenos Aires, Argentina.
Bárbara Costa BeberDepartment of Speech and Language Pathology, Atlantic Fellow for Equity in Brain Health, Federal University of Health Sciences of Porto Alegre (UFCSPA), Porto Alegre, Brazil.
Felipe A CourtCenter for Integrative Biology, Faculty of Sciences, FONDAP Center for Geroscience, Brain Health and Metabolism, Santiago, Chile, The Buck Institute for Research on Aging, Universidad Mayor, Chile, Novato, CA, USA.
Leonardo Cruz de SouzaFaculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Nilton CustodioUnit Cognitive Impairment and Dementia Prevention, Cognitive Neurology Center, Peruvian Institute of Neurosciences, Lima, Perú.
Andres DamianCentro Uruguayo de Imagenología Molecular (CUDIM), Centro de Medicina Nuclear e Imagenología Molecular, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay.
Myriam de la CruzGlobal Brain Health Institute, University of California, San Francisco, USA.
Roberta Diehl RodriguezBehavioral and Cognitive Neurology Unit, Department of Neurology and LIM 22, University of São Paulo, São Paulo, Brazil.
Sonia Maria Dozzi BruckiCognitive and Behavioral Neurology Group, University of Sao Paulo, São Paulo, Brazil.
Lais FajersztajnLaboratory of Experimental Air Pollution (LIM05), Department of Pathology, School of Medicine, Global Brain Health Institute, University of California, San Francisco (UCSF), University of São Paulo, São Paulo, Sao Paulo, Brazil.
Gonzalo A FaríasDepartment Neurology and Neurosurgery North/Department of Neurosciences, Center for Advanced Clinical Research (CICA), Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Fernanda G De FeliceFederal University of Rio de Janeiro, Brazil/Queen's University, Canada.
Raffaele FerrariDepartment of Neurodegenerative Disease, University College London, London, ES, UK.
Fabricio Ferreira de OliveiraDepartment of Neurology and Neurosurgery, Escola Paulista de Medicina, Federal University of São Paulo - UNIFESP, São Paulo, Brazil.
Sergio T FerreiraInstitute of Medical Biochemistry Leopoldo de Meis & Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Ceres FerrettiDivision of Neurology, University of São Paulo, São Paulo, Brazil.
Marcio Luiz Figueredo BalthazarDepartment of Neurology, University of Campinas (UNICAMP), Brazil.
Norberto Anizio Ferreira FrotaHospital Geral de Fortaleza, University of Fortaleza, Brazil.
Patricio FuentesGeriatrics Section Clinical Hospital University of Chile, Santos Dumont 999 Independencia, Santiago, Chile.
Adolfo M GarcíaCognitive Neuroscience Center (CNC), Faculty of Education, National University of Cuyo (UNCuyo), Universidad de San Andres. National Scientific and Technical Research Council (CONICET), Mendoza, Argentina.
Patricia J GarciaSchool of Public Health, Cayetano Heredia University.
Fábio Henrique de Gobbi PortoLaboratory of Psychiatric Neuroimaging (LIM-21), Instituto de Psiquiatria, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil.
Lissette Duque PeñaililloMemory Clinic, Neuromedicenter, Ecuadorian Dementia Association, Quito, Ecuador.
Henry Willy EnglerFacultad de Medicina de la Universidad de la República, Montevideo, Uruguay.
Irene MaierAltoida Inc., Houston, Texas, USA.
Ignacio F MataDepartment of Genomic Medicine, Lerner Research Institute, Cleveland Clinic, OH, USA.
Christian Gonzalez-BillaultCenter for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile, and Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile.
Oscar L LopezAlzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA, USA.
Laura MorelliFundacion Instituto Leloir-IIBBA-CONICET. Ave, Argentina.
Ricardo NitriniDepartment of Neurology, University of São Paulo Medical School, São Paulo, Brazil.
Yakeel T QuirozMassachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Alejandra Guerrero BarraganTrinity College Dublin, Dublin, Departamento de Neurologia Hospital Occidente de Kennedy, Global Brain Health Institute, Universidad de la Sabana, Bogota, Colombia.
David HuepeCenter for Social and Cognitive Neuroscience (CSCN), School of Psychology, Universidad Adolfo Ibañez, Santiago, Chile.
Fabricio Joao PioDepartment of Neurology, Hospital Governador Celso Ramos, Florianopolis, Brazil.
Claudia Kimie SuemotoDivision of Geriatrics, University of Sao Paulo, Sao Paulo, Brazil.
Renata KochhannGraduate Program in Psychology, School of Health Sciences, Hospital Moinhos de Vento, Pontifical Catholic University of Rio Grande do Sul-PUCRS and Researcher Office, Porto Alegre, Brazil.
Silvia KochenNeurosciences and Complex Systems Unit (EnyS), CONICET, Hosp, El Cruce "N. Kirchner", Univ. National A, Jauretche (UNAJ), F. Varela, Prov. Buenos Aires. Fac. Medicine, Univ Nacional de Buenos Aires (UBA), Buenos Aires, Argentina.
Fiona KumforBrain and Mind Centre and School of Psychology, University of Sydney, Sydney, NSW, Australia.
Serggio LanataUCSF Department of Neurology, Memory and Aging Center, UCSF, San Francisco, California, US.
Bruce MillerUCSF Department of Neurology, Memory and Aging Center, UCSF, San Francisco, California, US.
Leticia Lessa Mansur[deceased] São Paulo University, São Paulo, Brazil.
Mirna Lie HosogiBehavioral and Cognitive Unit of Department of Neurology, University of São Paulo School of Medicine, Sao Paulo, Brazil.
Patricia LilloGeroscience Center for Brain Health and Metabolism, Santiago, Chile, Departamento de Neurología Sur/Departamento de Neurociencia, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Jorge Llibre GuerraGlobal Brain Health Institute, UCSF, California, US.
David LiraUnit Cognitive Impairment and Dementia Prevention, Cognitive Neurology Center, Peruvian Institute of Neurosciences, Lima, Perú.
Francisco LoperaNeuroscience Research Group, Universidad de Antioquia, Medellín, Colombia.
Adelina ComasDepartment of Health Policy at the London School of Economics and Political Science, London, UK.
José Alberto Avila-FunesInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.
Ana Luisa SosaInstituto Nacional de Neurología y Neurocirugía, Ciudad de México, México.
Claudia RamosGlobal Brain Health Institute, University of California, San Francisco (UCSF), San Francisco, USA.
Elisa de Paula França ResendeGlobal Brain Health Institute, University of California, San Francisco (UCSF), San Francisco, USA.
Heather M SnyderDivision of Medical and Scientific Relations, Alzheimer's Association.
Ioannis TarnanasGlobal Brain Health Institute, University of California, San Francisco, USA.
Jenifer YokoyamaUCSF Department of Neurology, Memory and Aging Center, UCSF, San Francisco, California, US.
Juan LlibreCentro de estudios de Alzheimer, Cuba.
Juan Felipe CardonaUniversidad del Valle, Cali, Colombia, USA.
Kate PossinUCSF Department of Neurology, Memory and Aging Center, UCSF, San Francisco, California, US.
Kenneth S KosikNeuroscience Research Institute and Dept of Molecular Cellular and Developmental Biology, University of California Santa, Barbara, California, USA.
Rosa MontesinosUnit Cognitive Impairment and Dementia Prevention, Cognitive Neurology Center, Peruvian Institute of Neurosciences, Lima, Perú.
Sebastian MoguilnerGlobal Brain Health Institute, University of California, San Francisco (UCSF), San Francisco, USA.
Patricia Cristina Lourdes SolisNeurosciences and Complex Systems Unit (EnyS), CONICET, Hosp, El Cruce "N. Kirchner", Univ. National A, Jauretche (UNAJ), F. Varela, Prov. Buenos Aires. Fac. Medicine, Univ Nacional de Buenos Aires (UBA), Buenos Aires, Argentina.
Renata Eloah de Lucena Ferretti-RebustiniMedical-surgical Nursing Department, University of São Paulo School of Nursing, São Paulo, Brazil.
Jeronimo Martin RamirezDepartamen de Admision Continua Adultos Hospital General La Raza Instituto Mexicano del Seguro Social, Global Brain Health Institute, Trinity College Dublin, Dublin, Ciudad de Mexico, Mexico.
Diana MatallanaMedical School, Aging Institute and Psychiatry Department, Pontificia Universidad Javeriana. Memory and Cognition Center-Intellectus, Hospital Universitario San Ignacio, Bogotá, Colombia.
Lingani Mbakile-MahlanzaGlobal Brain Health Institute, University of California San Francisco, University of Botswana, Gaborone, Botswana.
Alyne Mendonça Marques TonLaboratory of Translational Medicine, Vila Velha University, Espírito Santo, Brazil.
Ronnielly Melo TavaresBehavioral Neurology Clinic Santa Casa de Belo Horizonte, MG, Brazil.
Eliane C MiottoDepartment of Neurology, University of Sao Paulo, Sao Paulo, Brazil.
Graciela Muniz-TerreraCentre for Dementia Prevention, University of Edinburgh, Scotland, UK.
Luis Arnoldo Muñoz-NevárezGlobal Brain Health Institute, University of California San Francisco, San Francisco, USA.
David OrozcoCognitive Neuroscience Development Laboratory, Axis Neurociencias, Universidad Nacional del Sur, Cognitive Impairment and Behavior Disorders Unit, Bahía Blanca, Argentina.
Maira Okada de OliveiraGlobal Brain Health Institute, University of California, San Francisco (UCSF), San Francisco, USA.
Olivier PiguetSchool of Psychology and Brain and Mind Centre, University of Sydney, Camperdown, NSW, Australia.
Maritza Pintado CaipaGlobal Brain Health Institute, University of California, San Francisco (UCSF), San Francisco, USA.
Stefanie Danielle Piña EscuderoGlobal Brain Health Institute, University of California, San Francisco (UCSF), San Francisco, USA.
Lucas Porcello SchillingDepartment of Neurology, Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
André Luiz Rodrigues PalmeiraSanta Casa de Misericórdia de Porto Alegre, Serviço de Neurologia, Porto Alegre, Brazil, Hospital Ernesto Dornelles, Serviço de Neurologia e Neurocirurgia, Porto Alegre, Brazil.
Mônica Sanches YassudaSchool of Arts, Sciences and Humanities, University of São Paulo, São Paulo, Brazil.
Jose Manuel Santacruz-EscuderoMedical School and Psychiatry Department, Memory and Cognition Center- Intellectus, Pontificia Universidad Javeriana, Hospital Universitario San Ignacio, Bogotá, Colombia.
Rodrigo Bernardo SerafimFederal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Jerusa SmidDepartment of Neurology, University of Sao Paulo, São Paulo, Brazil.
Andrea SlachevskyNeurology Department, Geroscience Center for Brain Health and Metabolism, Santiago, Chile, Laboratory of Neuropsychology and Clinical Neuroscience (LANNEC), Physiopathology Program-ICBM, East Neurologic and Neurosciences Departments, Faculty of Medicine, Hospital del Salvador and Faculty of Medicine University of Chile. Servicio de Neurología, Departamento de Medicina, Clínica Alemana-Universidad del Desarrollo, University of Chile, Neuropsychiatry and Memory Disorders clinic (CMYN), Santiago, Chile.
Cecilia SerranoMemory and Balance Clinic, Buenos Aires, Argentina.
Marcio Soto-AñariUniversidad Católica San Pablo, Arequipa, Perú.
Leonel Tadao TakadaHospital das Clinicas, University of Sao Paulo Medical School, Brazil.
Lea Tenenholz GrinbergDepartments of Neurology, Pathology and Global Brain Health Institute, UCSF - USA, Department of Pathology, University of São Paulo Medical School, São Paulo, Brazil.
Antonio Lucio TeixeiraLaboratório Interdisciplinar de Investigação Médica, Faculdade de Medicina, Av. Alfredo Balena, 110, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Maira Tonidandel BarbosaFaculdade de Medicina da Universidade Federal de Minas Gerais e Faculdade deCiências Médicas de Minas Gerais, Belo Horizonte, Brazil.
Dominic TrépelGlobal Brain Health Institute (GBHI), Trinity College Dublin, Dublin.
Agustin IbanezCognitive Neuroscience Center (CNC) Buenos Aires, Argentina; Universidad Autonoma del Caribe, Barranquilla, Colombia; Global Brain Health Institute (GBHI), US, Universidad de San Andres, CONICET, Universidad Autonoma del Caribe, Universidad Adolfo Ibanez, UCSF, USA.ORCID 0000-0001-6758-5101
Funding
US-South American Initiative for Genetic-Neural-Behavioral Interactions in Human Neurodegenerative ResearchR01AG057234 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Claudia Duran-Aniotz, Agustin M. Ibanez · 2019 to 2026
$6.1MMedical Research Council MR/K026992/1NIA NIH HHS R01 AG057234
Abstract
Across Latin American and Caribbean countries (LACs), the fight against dementia faces pressing challenges, such as heterogeneity, diversity, political instability, and socioeconomic disparities. These can be addressed more effectively in a collaborative setting that fosters open exchange of knowledge. In this work, the Latin American and Caribbean Consortium on Dementia (LAC-CD) proposes an agenda for integration to deliver a Knowledge to Action Framework (KtAF). First, we summarize evidence-based strategies (epidemiology, genetics, biomarkers, clinical trials, nonpharmacological interventions, networking, and translational research) and align them to current global strategies to translate regional knowledge into transformative actions. Then we characterize key sources of complexity (genetic isolates, admixture in populations, environmental factors, and barriers to effective interventions), map them to the above challenges, and provide the basic mosaics of knowledge toward a KtAF. Finally, we describe strategies supporting the knowledge creation stage that underpins the translational impact of KtAF.
Indexed as
Evidence-Based PracticeBiomarkersDementiaHumansLatin AmericaSocioeconomic FactorsBiomarkersbiomarkersclinical trialsdementiaepidemiologyevidence-based recommendationsgeneticsknowledge to action frameworkLatin Americanetworking and translational researchnonpharmacological interventions
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