Evidence map›Paper›PMID 33634593›Full record

ArticleESC heart failure2021

Stroke and systemic embolism in patients with atrial fibrillation and heart failure according to heart failure type.

Jae-Sun Uhm, Jun Kim, Hee Tae Yu, Tae-Hoon Kim, So-Ryoung Lee, Myung-Jin Cha, Eue-Keun Choi, Jung Myung Lee, Jin-Bae Kim, Junbeom Park and 9 more

Abstract readMulticenter Study
In one paragraph

Article in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jae-Sun UhmDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro Seodaemun-gu, Seoul, 03722, South Korea.ORCID 0000-0002-1611-8172
Jun KimDivision of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.ORCID 0000-0002-3573-638X
Hee Tae YuDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro Seodaemun-gu, Seoul, 03722, South Korea.ORCID 0000-0002-6835-4759
Tae-Hoon KimDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro Seodaemun-gu, Seoul, 03722, South Korea.ORCID 0000-0003-4200-3456
So-Ryoung LeeDepartment of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.ORCID 0000-0002-6351-5015
Myung-Jin ChaDepartment of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.ORCID 0000-0001-6180-0157
Eue-Keun ChoiDepartment of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.ORCID 0000-0002-0411-6372
Jung Myung LeeDivision of Cardiology, Kyung Hee University Hospital, Seoul, South Korea.ORCID 0000-0002-1904-5335
Jin-Bae KimDivision of Cardiology, Kyung Hee University Hospital, Seoul, South Korea.ORCID 0000-0002-0293-0901
Junbeom ParkDepartment of Cardiology, College of Medicine, Ewha Woman's University, Seoul, South Korea.ORCID 0000-0003-2192-9401
Jin-Kyu ParkDivision of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine, Seoul, South Korea.ORCID 0000-0001-7931-777X
Ki-Woon KangDivision of Cardiology, Eulji University Hospital, Daejeon, South Korea.ORCID 0000-0002-1361-0022
Jaemin ShimArrhythmia Center, Korea University Medical Center Anam Hospital, Seoul, South Korea.ORCID 0000-0001-8251-1522
Hyung Wook ParkDepartment of Cardiovascular Medicine, The Heart Center of Chonnam National University Hospital, Gwangju, South Korea.ORCID 0000-0002-9630-0467
Young Soo LeeDepartment of Cardiology, College of Medicine, Catholic University of Daegu, Daegu, South Korea.
Chang-Soo KimDepartment of Preventive Medicine, Yonsei University College of Medicine, Seoul, South Korea.
Ji Eun MunData Science Team, Center for Digital Health, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, South Korea.
Nak-Hoon SonData Science Team, Center for Digital Health, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, South Korea.ORCID 0000-0002-6192-8852
Boyoung JoungDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro Seodaemun-gu, Seoul, 03722, South Korea.ORCID 0000-0001-9036-7225

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study aimed to elucidate the risk for stroke and systemic embolism (SE) in patients with atrial fibrillation and heart failure (HF) according to HF type. METHODS AND

resultsA total of 10 780 patients with atrial fibrillation were enrolled in a multicentre prospective registry and divided according to HF type: no-HF, HF with preserved ejection fraction (EF) (HFpEF), HF with mid-range EF (HFmrEF), and HF with reduced EF (HFrEF). Each group included 237 age-matched and sex-matched patients (age, 69.0 ± 10.3 years; men, 69.6%). The baseline characteristics, cumulative incidence, and hazard ratios for stroke/SE and major bleeding were compared across the groups. Patients with HF accounted for 10.3% of the total population; HFpEF, HFmrEF, and HFrEF represented 43.7%, 23.6%, and 32.7% of the patients with HF, respectively. The CHA

conclusionsThe stroke/SE risk was the highest in the HFpEF group and comparable between the HFmrEF and HFrEF groups.

Indexed as

Atrial FibrillationEmbolismHeart FailureStrokeAgedHumansMaleMiddle AgedPrognosisStroke VolumeAtrial fibrillationBleedingEjection fractionHeart failureStrokeSystemic embolism

Identifiers

PMID33634593
PMCPMC8006674

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.