ArticleCurrent microbiology2021
Identification and Characterization of Polyphenols from Carissa spinarum Fruit and Evaluation of Their Antioxidant and Anti-quorum Sensing Activity.
Article in Current microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 23 citations in OpenAlex.
- Discovery of dietary polyphenols targeting the autoinducer-2 quorum sensing system of pathogenic bacteria.Gut microbes · 2026Article
- Probiotic-Plant Bioactive Synergy in Gut Health: Mechanisms, Antimicrobial Activity, and Translational Challenges.Nutrients · 2026Review
- Phenolic-Rich Wine Pomace Extracts as Antioxidant and Antipathogenic Agents AgainstAntibiotics (Basel, Switzerland) · 2025Article
- Exploring the potential ofJournal of food science and technology · 2025Article
- Ethnobotanical study of wild edible plants in Arsi Robe district of East Arsi Zone, Ethiopia.Journal of ethnobiology and ethnomedicine · 2024Article
- Polyphenolic compounds in the combat of foodborne infections - An update on recent evidence.European journal of microbiology & immunology · 2024Review
- Polyphenols and CRISPR as Quorum Quenching Agents in Antibiotic-Resistant Foodborne Human Pathogens (Foods (Basel, Switzerland) · 2024Review
- Phytonutritional and Sensorial Assessment of a Novel Functional Beverage Formulated from an Underutilized Fruit ofACS omega · 2023Article
- Article
- Physicochemical Composition and Characterization of Bioactive Compounds of Mulberry (Morus indica L.) Fruit During Ontogeny.Plant foods for human nutrition (Dordrecht, Netherlands) · 2021Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Quorum sensing controls bacterial virulence through signaling molecules, which plays a vital role in managing foodborne pathogens that cause food spoilage and human infections. Though many synthetic compounds have been used to control infection, antibiotic resistance has become a global issue. Targeting the bacterial quorum sensing using the bioactive compounds could be an alternative strategy to combat their resistance. In this context, polyphenols from an unexplored unripe and ripe fruits of Carissa spinarum were evaluated for anti-quorum sensing activity. The study aimed at determining nutritional, phytochemical composition, and polyphenol profiling to evaluate their antioxidant potential of the fruit. Furthermore, the violacein inhibition, anti-biofilm, and effect on the motility of foodborne pathogens were also studied. The phytochemical content of C. spinarum fruit showed the phenolic and flavonoid content 273.20 mg GAE/100 g and 453.78 mg QE/100 g fresh weight , respectively, in ripe fruit. HPLC characterization of fruit extracts showed high content of syringic acid, resveratrol, and quercetin in ripe, whereas it showed epicatechin and gentisic acid in unripe fruit. The antioxidant activity of the ripe fruit extract exhibited a higher potential to scavenge DPPH radicals with IC
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