Evidence map›Paper›PMID 33634264›Full record

ArticleCritical care explorations2021

Life Support Limitations in Mechanically Ventilated Stroke Patients.

Etienne de Montmollin, Carole Schwebel, Claire Dupuis, Maité Garrouste-Orgeas, Daniel da Silva, Elie Azoulay, Virginie Laurent, Guillaume Thiéry, Alexandra Grinea, Guillaume Marcotte and 9 more

Open access · goldAbstract read
In one paragraph

Article in Critical care explorations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 1 country.

Etienne de MontmollinUniversité de Paris, UMR 1137, IAME, Paris, France.
Carole SchwebelMedical ICU, Grenoble University Hospital, La Tronche, France.
Claire DupuisUniversité de Paris, UMR 1137, IAME, Paris, France.
Maité Garrouste-OrgeasMedical Unit, French British Hospital, Levallois-Perret, France.
Daniel da SilvaPolyvalent ICU, Delafontaine Hospital, Saint-Denis, France.
Elie AzoulayMedical ICU, Saint-Louis Hospital, Paris, France.
Virginie LaurentPolyvalent ICU, André Mignot Hospital, Le Chesnay, France.
Guillaume ThiéryPolyvalent ICU, Hôpital Nord, Saint-Etienne, France.
Alexandra GrineaAssistance Publique - Hopitaux de Paris, Medical and Infectious Diseases ICU, Bichat-Claude Bernard Hospital, Paris, France.
Guillaume MarcotteSurgical ICU, Edouard Herriot Hospital, Lyon, France.
Johanna OzielAssitance Publique - Hopitaux de Paris, Polyvalent ICU, Avicenne Hospital, Bobigny, France.
Marc GainnierMedical ICU, La Timone Hospital, Marseille, France.
Shidasp SiamiPolyvalent ICU, Sud-Essonne Hospital, Etampes, France.
Jean ReignierMedical ICU, Nantes University Hospital, Nantes, France.
Benjamin SztrymfAssistance Publique - Hopitaux de Paris, Polyvalent ICU, Antoine Béclère Hospital, Clamart, France.
Christophe AdrieAssistance Publique - Hopitaux de Paris, Physiology Department, Cochin Hospital, Paris, France.
Stephane RucklyUniversité de Paris, UMR 1137, IAME, Paris, France.
Romain SonnevilleAssistance Publique - Hopitaux de Paris, Medical and Infectious Diseases ICU, Bichat-Claude Bernard Hospital, Paris, France.
Jean-François TimsitUniversité de Paris, UMR 1137, IAME, Paris, France.
Université Paris Cité · FRCentre Hospitalier Saint-Denis · FRHôpital Saint-Louis · FRInstitut Hospitalier Franco Britannique · FRMelun Hospital · FRNantes Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe determinants of decisions to limit life support (withholding or withdrawal) in ventilated stroke patients have been evaluated mainly for patients with intracranial hemorrhages. We aimed to evaluate the frequency of life support limitations in ventilated ischemic and hemorrhagic stroke patients compared with a nonbrain-injured population and to determine factors associated with such decisions.

designMulticenter prospective French observational study.

settingFourteen ICUs of the French OutcomeRea network. PATIENTS: From 2005 to 2016, we included stroke patients and nonbrain-injured patients requiring invasive ventilation within 24 hours of ICU admission.

interventionNone. MEASUREMENTS AND MAIN

resultsWe identified 373 stroke patients (ischemic,

conclusionsIn ventilated stroke patients, decisions to limit life support are more than three times more frequent than in nonbrain-injured patients, with different timing and associated risk factors between ischemic and hemorrhagic strokes.

Indexed as

critical careend-of-life careintracerebral hemorrhageischemic strokesubarachnoid hemorrhage

Identifiers

PMID33634264
PMCPMC7901798
OpenAlexW3131038790

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.