Evidence map›Paper›PMID 33634165›Full record

ArticleFrontiers in molecular biosciences2020

Silencing of the tRNA Modification Enzyme Cdkal1 Effects Functional Insulin Synthesis in NIT-1 Cells: tRNA

Amithi Narendran, Sweta Vangaveti, Srivathsan V Ranganathan, Emily Eruysal, Miranda Craft, Omar Alrifai, Fu Yee Chua, Kathryn Sarachan, Breann Litwa, Sheetal Ramachandran and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular biosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Amithi NarendranThe RNA Institute and Department of Biological Sciences, University of Albany, Albany, NY, United States.
Sweta VangavetiProgram in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, MA, United States.
Srivathsan V RanganathanKnight Cancer Institute, Oregon Health Sciences, School of Medicine, Portland, OR, United States.
Emily EruysalThe RNA Institute and Department of Biological Sciences, University of Albany, Albany, NY, United States.
Miranda CraftThe RNA Institute and Department of Biological Sciences, University of Albany, Albany, NY, United States.
Omar AlrifaiThe RNA Institute and Department of Biological Sciences, University of Albany, Albany, NY, United States.
Fu Yee ChuaThe RNA Institute and Department of Biological Sciences, University of Albany, Albany, NY, United States.
Kathryn SarachanThe RNA Institute and Department of Biological Sciences, University of Albany, Albany, NY, United States.
Breann LitwaThe RNA Institute and Department of Biological Sciences, University of Albany, Albany, NY, United States.
Sheetal RamachandranDepartment of Medicine, Duke University School of Medicine, Durham, NC, United States.
Paul F AgrisThe RNA Institute and Department of Biological Sciences, University of Albany, Albany, NY, United States.
Duke University · USOHSU Knight Cancer InstituteUniversity of Massachusetts Chan Medical School · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human Genome Wide Association Studies found a significant risk of Type 2 Diabetes Mellitus (T2DM) in single nucleotide polymorphisms in the

Indexed as

CDKAL1Cdkal1 proteininsulintRNA modificationType 2 diabetesWobble decoding on the ribosome

Identifiers

PMID33634165
PMCPMC7900539
OpenAlexW3128322117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.