Evidence map›Paper›PMID 33633584›Full record

ArticleFrontiers in physiology2021

Inhibition of Small-Conductance Calcium-Activated Potassium Current (

Merle Friederike Fenner, Giulia Gatta, Stefan Sattler, Marion Kuiper, Eva Melis Hesselkilde, Ditte M T Adler, Morten Smerup, Ulrich Schotten, Ulrik Sørensen, Jonas Goldin Diness and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Small-Conductance CaNeuroscience bulletin · 2026
    Review
  2. Article
  3. Metformin Protects Against Persistent Atrial Fibrillation in an Equine Model.Circulation. Arrhythmia and electrophysiology · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Muscarinic acetylcholine receptors MFrontiers in cardiovascular medicine · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Merle Friederike FennerDepartment of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Taastrup, Denmark.
Giulia GattaDepartment of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands.
Stefan SattlerDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Marion KuiperDepartment of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands.
Eva Melis HesselkildeDepartment of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Taastrup, Denmark.
Ditte M T AdlerDepartment of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Taastrup, Denmark.
Morten SmerupDepartment of Cardiothoracic Surgery, The Heart Centre, Copenhagen University Hospital, Copenhagen, Denmark.
Ulrich SchottenDepartment of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands.
Ulrik SørensenAcesion Pharma ApS, Copenhagen, Denmark.
Jonas Goldin DinessAcesion Pharma ApS, Copenhagen, Denmark.
Thomas JespersenDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Sander VerheuleDepartment of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands.
Arne Van HunnikDepartment of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands.
Rikke BuhlDepartment of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Taastrup, Denmark.
University of Copenhagen · DKMaastricht University · NLAcesion Pharma (Denmark) · DKCopenhagen University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSmall-conductance Ca EXPERIMENTAL APPROACH AND

methodsTo address the hypothesis of the efficacy of

results

conclusionsIntra-atrial heterogeneity in response to

Indexed as

AF conductionatrial selectivityepicardial contact mappingequine/horse modelinter-atrial heterogeneityNS8593persistent atrial fibrillationSK/KCa2 channels

Identifiers

PMID33633584
PMCPMC7900437
OpenAlexW3126209205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.