Evidence map›Paper›PMID 33633567›Full record

ArticleFrontiers in pharmacology2020

Deletion of Orphan G Protein-Coupled Receptor GPR37L1 in Mice Alters Cardiovascular Homeostasis in a Sex-Specific Manner.

Margaret A Mouat, Kristy L Jackson, James L J Coleman, Madeleine R Paterson, Robert M Graham, Geoffrey A Head, Nicola J Smith

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Rare GPR37L1 Variants Reveal Potential Association between GPR37L1 and Disorders of Anxiety and Migraine.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  3. Role of G-protein coupled receptors in cardiovascular diseases.Frontiers in cardiovascular medicine · 2023
    Review
  4. Article
  5. Impaired Aversive Memory Formation in GPR37L1KO Mice.International journal of molecular sciences · 2022
    Article
  6. Article
  7. Mouse Mutants ofInternational journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Margaret A MouatMolecular Pharmacology Laboratory, Victor Chang Cardiac Research Institute, Sydney, NSW, Australia.
Kristy L JacksonNeuropharmacology Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
James L J ColemanMolecular Pharmacology Laboratory, Victor Chang Cardiac Research Institute, Sydney, NSW, Australia.
Madeleine R PatersonNeuropharmacology Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Robert M GrahamSt Vincent's Clinical School, UNSW Sydney, Sydney, NSW, Australia.
Geoffrey A HeadNeuropharmacology Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Nicola J SmithMolecular Pharmacology Laboratory, Victor Chang Cardiac Research Institute, Sydney, NSW, Australia.
Baker Heart and Diabetes Institute · AUSt Vincent's Clinic · AUUNSW Sydney · AUVictor Chang Cardiac Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GPR37L1 is a family A orphan G protein-coupled receptor (GPCR) with a putative role in blood pressure regulation and cardioprotection. In mice, genetic ablation of

Indexed as

blood pressureG protein-coupled receptorheart rate variabilityhypertensionradiotelemetrysex differences

Identifiers

PMID33633567
PMCPMC7901490
OpenAlexW3126740463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.