Evidence map›Paper›PMID 33633200›Full record

ArticleScientific reports2021

Role of sex in the association between childhood socioeconomic position and cognitive ageing in later life.

Katrin Wolfova, Zsofia Csajbok, Anna Kagstrom, Ingemar Kåreholt, Pavla Cermakova

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. The Interplay of Genes and Environment Across Multiple Studies (IGEMS) Consortium After Fifteen Years.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2026
    Article
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  4. Review
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  6. Observational
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  8. Article
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  10. Review
  11. Impact of childhood and adult socioeconomic position on change in functional aging.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024
    Article
  12. Cumulative Stress Exposure and Cognitive Function Among Older Adults: The Moderating Role of a Healthy Lifestyle.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023
    Article
  13. Childhood Socioeconomic Disadvantage and Pathways to Memory Performance in Mid to Late Adulthood: What Matters Most?The journals of gerontology. Series B, Psychological sciences and social sciences · 2022
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Katrin WolfovaDepartment of Psychiatry and Medical Psychology, Third Faculty of Medicine, Charles University in Prague, Ruska 87, 100 00, Prague 10, Czech Republic.ORCID 0000-0003-0295-8848
Zsofia CsajbokDepartment of Psychiatry and Medical Psychology, Third Faculty of Medicine, Charles University in Prague, Ruska 87, 100 00, Prague 10, Czech Republic.ORCID 0000-0002-5800-1597
Anna KagstromDepartment of Psychiatry and Medical Psychology, Third Faculty of Medicine, Charles University in Prague, Ruska 87, 100 00, Prague 10, Czech Republic.ORCID 0000-0002-1455-1300
Ingemar KåreholtInstitute of Gerontology, Aging Research Network - Jönköping (ARN-J), School of Health and Welfare, Jönköping University, Jönköping, Sweden.ORCID 0000-0002-8617-0355
Pavla CermakovaDepartment of Psychiatry and Medical Psychology, Third Faculty of Medicine, Charles University in Prague, Ruska 87, 100 00, Prague 10, Czech Republic. Pavla.Cermakova@nudz.cz.ORCID 0000-0002-9282-9363

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Understanding and Improving Healthcare Decision-Making and Outcomes for People Living with Alzheimer's Disease and Related DementiasP01AG005842 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI KOSALI ILAYPERUMA SIMON · 1986 to 2026
$56.5M
WEALTH DISPARITIES AMONG MATURE AND OLDER ADULTSP01AG008291 · NIA · RAND CORPORATION · PI HURD, MICHAEL D · 1989 to 2018
$19.4M
RAND CENTER FOR THE STUDY OF AGINGP30AG012815 · NIA · RAND CORPORATION · PI HURD, MICHAEL D · 1999 to 2020
$13.7M
DEVELOPING AN ISRAELI VERSION OF THE HRS/SHARE PROJECTR21AG025169 · NIA · HEBREW UNIVERSITY OF JERUSALEM · PI LITWIN, HOWARD · 2004 to 2006
$297k
NIA NIH HHS HHSN271201300071CNIA NIH HHS P01 AG005842NIA NIH HHS P01 AG008291NIA NIH HHS P30 AG012815NIA NIH HHS R21 AG025169NIA NIH HHS U01 AG009740
6 · The paper itself

Abstract

We aimed to explore sex differences in the association of childhood socioeconomic position (SEP) with the level of cognitive performance and the rate of cognitive decline. We studied 84,059 individuals (55% women; mean age 64 years) from the Survey on Health, Ageing and Retirement in Europe. Sex differences in the association of childhood SEP (household characteristics at age 10) with the level of cognitive performance (verbal fluency, immediate recall, delayed recall) were analysed using multilevel linear regression. Structural equation modelling tested education, depressive symptoms and physical state as mediators. The relationship between childhood socioeconomic advantage and disadvantage and the rate of cognitive decline was assessed using linear mixed-effects models. Higher childhood SEP was associated with a higher level of cognitive performance to a greater extent in women (B = 0.122; 95% CI 0.092-0.151) than in men (B = 0.109; 95% CI 0.084-0.135). The strongest mediator was education. Childhood socioeconomic disadvantage was related to a higher rate of decline in delayed recall in both sexes, with a greater association in women. Strategies to prevent impaired late-life cognitive functioning, such as reducing childhood socioeconomic disadvantages and improving education, might have a greater benefit for women.

Indexed as

Sex FactorsSocial ClassAgedAgingChildCognitionCross-Sectional StudiesDepressionEducational StatusFemaleHumansLongitudinal StudiesMaleMiddle Aged

Identifiers

PMID33633200
PMCPMC7907064

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.