Evidence map›Paper›PMID 33633131›Full record

ArticleScientific reports2021

A spatiotemporal analysis of opioid poisoning mortality in Ohio from 2010 to 2016.

Chihyun Park, Jean R Clemenceau, Anna Seballos, Sara Crawford, Rocio Lopez, Tyler Coy, Gowtham Atluri, Tae Hyun Hwang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Opioid Overdose Death Prediction with Graph Neural Networks.medRxiv : the preprint server for health sciences · 2026
    Article
  3. Article
  4. Opioid Overdose Death Prediction with Graph Neural Networks.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026
    Article
  5. Article
  6. A spatiotemporal analysis of opioid prescriptions in Indiana from 2015 to 2019.Substance abuse treatment, prevention, and policy · 2025
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Chihyun Park *Department of Quantitative Health Sciences (QHS), Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Jean R Clemenceau *Department of Quantitative Health Sciences (QHS), Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Anna SeballosDepartment of Quantitative Health Sciences (QHS), Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Sara CrawfordDepartment of Quantitative Health Sciences (QHS), Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Rocio LopezDepartment of Quantitative Health Sciences (QHS), Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Tyler CoyDepartment of Quantitative Health Sciences (QHS), Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Gowtham AtluriDepartment of Electrical Engineering and Computer Science (EECS), University of Cincinnati, P.O. Box 210030, Cincinnati, OH, 45221, USA. gowtham.atluri@uc.edu.
Tae Hyun HwangDepartment of Quantitative Health Sciences (QHS), Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA. hwangt@ccf.org.
Cleveland Clinic Lerner College of Medicine · USUniversity of Cincinnati · US

Funding

Molecular Medicine Training ProgramT32GM088088 · NIGMS · CLEVELAND CLINIC LERNER COM-CWRU · PI SMITH, JONATHAN D · 2011 to 2020
$1.7M
NIGMS NIH HHS T32 GM088088
6 · The paper itself

Abstract

Opioid-related deaths have severely increased since 2000 in the United States. This crisis has been declared a public health emergency, and among the most affected states is Ohio. We used statewide vital statistic data from the Ohio Department of Health (ODH) and demographics data from the U.S. Census Bureau to analyze opioid-related mortality from 2010 to 2016. We focused on the characterization of the demographics from the population of opioid-related fatalities, spatiotemporal pattern analysis using Moran's statistics at the census-tract level, and comorbidity analysis using frequent itemset mining and association rule mining. We found higher rates of opioid-related deaths in white males aged 25-54 compared to the rest of Ohioans. Deaths tended to increasingly cluster around Cleveland, Columbus and Cincinnati and away from rural regions as time progressed. We also found relatively high co-occurrence of cardiovascular disease, anxiety or drug abuse history, with opioid-related mortality. Our results demonstrate that state-wide spatiotemporal and comorbidity analysis of the opioid epidemic could provide novel insights into how the demographic characteristics, spatiotemporal factors, and/or health conditions may be associated with opioid-related deaths in the state of Ohio.

Indexed as

AdultAnalgesics, OpioidDrug OverdoseEmergency Service, HospitalFemaleHumansMaleMiddle AgedOhioSpatio-Temporal AnalysisAnalgesics, Opioid

Identifiers

PMID33633131
PMCPMC7907120
OpenAlexW3129434205

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.