Evidence map›Paper›PMID 33633130›Full record

ArticleScientific reports2021

In-field stereotactic body radiotherapy (SBRT) reirradiation for pulmonary malignancies as a multicentre analysis of the German Society of Radiation Oncology (DEGRO).

Caroline John, Riccardo Dal Bello, Nicolaus Andratschke, Matthias Guckenberger, Judit Boda-Heggemann, Eleni Gkika, Frederick Mantel, Hanno M Specht, Carmen Stromberger, Franz Zehentmayr and 2 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

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  6. FLASH proton reirradiation, with or without hypofractionation, reduces chronic toxicity in the normal murine intestine, skin, and bone.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2025
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  13. Stereotactic lung reirradiation for local relapse: A case series.Clinical and translational radiation oncology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 3 countries.

Caroline JohnDepartment of Radiation Oncology, University Hospital Zürich, University of Zurich, Zurich, Switzerland.
Riccardo Dal BelloDepartment of Radiation Oncology, University Hospital Zürich, University of Zurich, Zurich, Switzerland.
Nicolaus AndratschkeDepartment of Radiation Oncology, University Hospital Zürich, University of Zurich, Zurich, Switzerland.
Matthias GuckenbergerDepartment of Radiation Oncology, University Hospital Zürich, University of Zurich, Zurich, Switzerland.
Judit Boda-HeggemannDepartment of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Eleni GkikaDepartment of Radiation Oncology, University Medical Center Freiburg, Freiburg, Germany.
Frederick MantelDepartment of Radiation Oncology, University Hospital Würzburg, Würzburg, Germany.
Hanno M SpechtClinic for Radiation Oncology Freising, Freising, Germany.
Carmen StrombergerDepartment of Radiation Oncology, Charite - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Franz ZehentmayrDepartment of Radiation Oncology, Paracelsus Medical University, Salzburg, Austria.
Oliver BlanckDepartment of Radiation Oncology, University Medical Center Schleswig-Holstein, Kiel, Germany.
Panagiotis BalermpasDepartment of Radiation Oncology, University Hospital Zürich, University of Zurich, Zurich, Switzerland. Panagiotis.balermpas@usz.ch.
University of Zurich · CHCharité - Universitätsmedizin Berlin · DEParacelsus Medical University · ATUniversitätsklinikum Würzburg · DEUniversity Hospital Heidelberg · DEUniversity Hospital of Zurich · CHUniversity Medical Center Freiburg · DEUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data of thoracic in-field reirradiation with two courses of stereotactic body radiotherapy (SBRT) is scarce. Aim of this study is to investigate feasibility and safety of this approach. Patients with a second course of thoracic SBRT and planning target volume (PTV) overlap were analyzed in this retrospective, multicenter study. All plans and clinical data were centrally collected. 27 patients from 8 centers have been amenable for evaluation: 12 with non-small-cell lung cancer, 16 with metastases, treated from 2009 (oldest first course) to 2020 (latest second course). A median dose of 38.5 Gy to the 65%-isodose over a median of 5 fractions was prescribed in the first course and 40 Gy in 5 fractions for the second SBRT-course. Median PTV of the second SBRT was 29.5 cm

Indexed as

AdultAgedAged, 80 and overFemaleGermanyHumansLung NeoplasmsMaleMiddle AgedRadiosurgeryRetrospective StudiesSalvage Therapy

Identifiers

PMID33633130
PMCPMC7907095
OpenAlexW3129275303

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.