ArticleThe European respiratory journal2021
Altered pulmonary blood volume distribution as a biomarker for predicting outcomes in COVID-19 disease.
Article in The European respiratory journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Beneficial Effect of COVID-19 Vaccination on Decreased Pulmonary Vascular and Airway Volumes of Patients with Long-COVID Syndrome.Medical sciences (Basel, Switzerland) · 2026Article
- Quantitative analysis of pulmonary vascular alterations in children with refractoryQuantitative imaging in medicine and surgery · 2025Article
- Oscillometry Longitudinal Data on COVID-19 Acute Respiratory Syndrome Treated with Non-Invasive Respiratory Support.Journal of clinical medicine · 2024Article
- Damage to endothelial barriers and its contribution to long COVID.Angiogenesis · 2024Review
- U-Net-based computed tomography quantification of viral pneumonia can predict fibrotic interstitial lung abnormalities at 3-month follow-up.Frontiers in medicine · 2024Article
- Sialylated Glycan Bindings from SARS-CoV-2 Spike Protein to Blood and Endothelial Cells Govern the Severe Morbidities of COVID-19.International journal of molecular sciences · 2023Review
- Quantitative Analysis for Lung Disease on Thin-Section CT.Diagnostics (Basel, Switzerland) · 2023Review
- Unraveling pathophysiologic mechanisms contributing to symptoms in patients with post-acute sequelae of COVID-19 (PASC): A retrospective study.Physiological reports · 2023Observational
- Coronavirus Disease-2019 Pneumonia: Clinical Manifestations.Clinics in chest medicine · 2023Review
- Review
- Chest CT Findings in Hospitalized Patients with SARS-CoV-2: Delta versus Omicron Variants.Radiology · 2023Article
- CT-derived measurements of pulmonary blood volume in small vessels and the need for supplemental oxygen in COVID-19 patients.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Relation of Pulmonary Diffusing Capacity Decline to HRCT and VQ SPECT/CT Findings at Early Follow-Up after COVID-19: A Prospective Cohort Study (The SECURe Study).Journal of clinical medicine · 2022Article
- Pulmonary Blood Volume Among Older Adults in the Community: The MESA Lung Study.Circulation. Cardiovascular imaging · 2022Article
- Pulmonary thromboembolic events in COVID-19-A systematic literature review.Pulmonary circulation · 2022Review
- Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: a global perspective.Nature reviews. Cardiology · 2022Review
- Different Methods to Improve the Monitoring of Noninvasive Respiratory Support of Patients with Severe Pneumonia/ARDS Due to COVID-19: An Update.Journal of clinical medicine · 2022Review
- Quantitative Computed Tomography Parameters in Coronavirus Disease 2019 Patients and Prediction of Respiratory Outcomes Using a Decision Tree.Frontiers in medicine · 2022Article
- Pathophysiology of pulmonary function anomalies in COVID-19 survivors.Breathe (Sheffield, England) · 2021Article
- COVID-19 pneumonia and the pulmonary vasculature: a marriage made in hell.The European respiratory journal · 2021Article
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9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEvidence suggests that vascular inflammation and thrombosis may be important drivers of poor clinical outcomes in patients with COVID-19. We hypothesised that a significant decrease in the percentage of blood volume in vessels with a cross-sectional area between 1.25 and 5 mm
methodsWe performed a retrospective analysis of chest CT scans from 10 hospitals across two US states in 313 COVID-19-positive and 195 COVID-19-negative patients seeking acute medical care.
resultsBV5% was predictive of outcomes in COVID-19 patients in a multivariate model, with a BV5% threshold below 25% associated with OR 5.58 for mortality, OR 3.20 for intubation and OR 2.54 for the composite of mortality or intubation. A model using age and BV5% had an area under the receiver operating characteristic curve of 0.85 to predict the composite of mortality or intubation in COVID-19 patients. BV5% was not predictive of clinical outcomes in patients without COVID-19.
conclusionsThe data suggest BV5% as a novel biomarker for predicting adverse outcomes in patients with COVID-19 seeking acute medical care.
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