Evidence map›Paper›PMID 33632208›Full record

ArticleMalaria journal2021

Mentorship on malaria microscopy diagnostic service in Ethiopia: baseline competency of microscopists and performance of health facilities.

Bokretsion Gidey, Desalegn Nega, Adugna Abera, Abnet Abebe, Sindew Mekasha, Geremew Tasew, Mebrahtom Haile, Dereje Dillu, Degu Mehari, Ashenafi Assefa and 14 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Malaria journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 3 institutions in 1 country.

Bokretsion GideyEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia. bokregidey@yahoo.com.
Desalegn NegaEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Adugna AberaEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Abnet AbebeEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Sindew MekashaEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Geremew TasewEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Mebrahtom HaileFederal Ministry of Health (FMoH), Sudan Street, PO Box 80002, Addis Ababa, Ethiopia.
Dereje DilluFederal Ministry of Health (FMoH), Sudan Street, PO Box 80002, Addis Ababa, Ethiopia.
Degu MehariFederal Ministry of Health (FMoH), Sudan Street, PO Box 80002, Addis Ababa, Ethiopia.
Ashenafi AssefaEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Wondimeneh LiknewEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Abeba G/TsadikEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Hussien MohammedEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Ermias WoldieEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Tsegaye GetachewEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Desalegn ArarsoEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Dereje YenealemEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Adisu KebedeEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Kebede EtanaFederal Ministry of Health (FMoH), Sudan Street, PO Box 80002, Addis Ababa, Ethiopia.
Gizachew KedidaEthiopian Medical Laboratory Associations (EMLA), Tewodros Square, PO Box: 4866, Addis Ababa, Ethiopia.
Hiwot SolomonFederal Ministry of Health (FMoH), Sudan Street, PO Box 80002, Addis Ababa, Ethiopia.
Getachew TolleraEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Adugna WoyessaEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Ebba AbateEthiopian Public Health Institute (EPHI), Patriot Street, Gulele Subcity, PO Box 1242, Addis Ababa, Ethiopia.
Ethiopian Public Health Institute · ETFederal Ministry of Health · ETEthiopian Public Health Association · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Ethiopia, malaria cases are declining as a result of proven interventions, and in 2017 the country launched a malaria elimination strategy in targeted settings. Accurate malaria diagnosis and prompt treatment are the key components of the strategy to prevent morbidity and stop the continuation of transmission. However, the quality of microscopic diagnosis in general is deteriorating as malaria burden declines. This study was carried out to evaluate the competency of microscopists and the performance of health facilities on malaria microscopic diagnosis.

methodsA cross-sectional study was conducted from 1 August to 30 September, 2019 in 9 regional states and one city administration. A standard checklist was used for on-site evaluation, archived patient slides were re-checked and proficiency of microscopists was tested using a WHO-certified set of slides from the national slide bank at the Ethiopian Public Health Institute (EPHI). The strength of agreement, sensitivity, specificity, and positive and negative predictive values were calculated.

resultsIn this study, 102 health facilities (84 health centres and 18 hospitals) were included, from which 202 laboratory professionals participated. In slide re-checking, moderate agreement (agreement (A): 76.0%; Kappa (K): 0.41) was observed between experts and microscopists on malaria detection in all health facilities. The sensitivity and specificity of routine slide reading and the re-checking results were 78.1 and 80.7%, respectively. Likewise, positive predictive value of 65.1% and negative predictive value of 88.8% were scored in the routine diagnosis. By panel testing, a substantial overall agreement (A: 91.8%; K: 0.79) was observed between microscopists and experts in detecting malaria parasites. The sensitivity and specificity in the detection of malaria parasites was 92.7 and 89.1%, respectively. In identifying species, a slight agreement (A: 57%; K: 0.18) was observed between microscopists and experts.

conclusionThe study found significant false positive and false negative results in routine microscopy on slide re-checking of Plasmodium parasites. Moreover, reduced grade in parasite species identification was reported on the panel tests. Implementing comprehensive malaria microscopy mentorship, in-service training and supportive supervision are key strategies to improve the overall performance of health facilities in malaria microscopy.

Indexed as

AdultCross-Sectional StudiesDiagnostic ServicesDiagnostic Tests, RoutineEthiopiaFemaleHealth FacilitiesHumansMalariaMaleMentorsMicroscopyMiddle AgedProfessional CompetenceSensitivity and SpecificityYoung AdultCompetencyExternal quality assuranceMalaria microscopyMentorshipRe-checking

Identifiers

PMID33632208
PMCPMC7908686
OpenAlexW3128340534

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.