Evidence map›Paper›PMID 33632162›Full record

ArticleBMC ophthalmology2021

A rare case of unilateral Cogan's anterior internuclear ophthalmoplegia, upgaze palsy and ataxia caused by dorsal tegmentum lesion at pontomesencephalic junction.

Yong Zheng Wai, Qi Xiong Ng, Tsu Hong Lim, Lik Thai Lim

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yong Zheng WaiQueen Elizabeth Hospital, Sabah, Malaysia.
Qi Xiong NgQueen Elizabeth Hospital, Sabah, Malaysia.
Tsu Hong LimQueen Elizabeth Hospital, Sabah, Malaysia.
Lik Thai LimUniversiti Malaysia Sarawak (UNIMAS), Kota Samarahan, Sarawak, Malaysia. ltlim@unimas.my.
Queen Elizabeth Hospital · MYUniversiti Malaysia Sarawak · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCogan's anterior internuclear ophthalmoplegia (INO) is characterized by INO with inability to converge and commonly thought to be due to rostral midbrain lesion. A lesion outside midbrain that causes unilateral Cogan's anterior INO combined with upgaze palsy and ataxia are rarely described. CASE PRESENTATION: A 67-year old male presented with left Cogan's anterior internuclear ophthalmoplegia (INO), left appendicular ataxia and bilateral upgaze palsy. A Magnetic Resonance Imaging (MRI) and Magnetic Resonance Angiography (MRA) brain showed a left dorsal tegmental infarct at the level of pontomesencephalic junction.

conclusionsThis case highlights the clinical importance of Cogan's anterior INO in combination with upgaze palsy and ataxia, and report possible site of lesion in patients with such constellation. Clinicians should consider looking for cerebellar signs in cases of Cogan's anterior INO, apart from just considering localizing the lesion at the midbrain.

Indexed as

Ocular Motility DisordersOphthalmoplegiaAgedAtaxiaHumansMagnetic Resonance ImagingMaleParalysisCogan’s anterior internuclear ophthalmoplegiaPontomesencephalic junction

Identifiers

PMID33632162
PMCPMC7908666
OpenAlexW3130647864

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.