ArticleBMC geriatrics2021
A practical laboratory index to predict institutionalization and mortality - an 18-year population-based follow-up study.
Article in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The frailty index based on laboratory test data as a tool to investigate the impact of frailty on health outcomes: a systematic review and meta-analysis.Age and ageing · 2023Pooled it
- Prognostic Value of Frailty Assessment Combining the Frailty Index Based on Laboratory Tests With the Clinical Frailty Scale in Patients With Acute Heart Failure.Journal of the American Heart Association · 2025Observational
- Relationship between the laboratory test-based frailty index and overall mortality in critically ill patients with acute pancreatitis: a retrospective study based on the MIMIC-IV database.Frontiers in medicine · 2025Article
- Machine learning analyses identify multi-modal frailty factors that selectively discriminate four cohorts in the Alzheimer's disease spectrum: a COMPASS-ND study.BMC geriatrics · 2023Article
- A novel easy-to-use index to predict institutionalization and death in older population - a 10-year population-based follow-up study.BMC geriatrics · 2023Article
- Letter to editor: is laboratory index really a practical and valid tool to predict mortality?BMC geriatrics · 2021Article
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13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreviously, several indexes based on a large number of clinical and laboratory tests to predict mortality and frailty have been produced. However, there is still a need for an easily applicable screening tool for every-day clinical practice.
methodsA prospective study with 10- and 18-year follow-ups. Fourteen common laboratory tests were combined to an index. Cox regression model was used to analyse the association of the laboratory index with institutionalization and mortality.
resultsThe mean age of the participants (n = 1153) was 73.6 (SD 6.8, range 64.0-100.0) years. Altogether, 151 (14.8%) and 305 (29.9%) subjects were institutionalized and 422 (36.6%) and 806 (69.9%) subjects deceased during the 10- and 18-year follow-ups, respectively. Higher LI (laboratory index) scores predicted increased mortality. Mortality rates increased as LI scores increased both in unadjusted and in age- and gender-adjusted models during both follow-ups. The LI did not significantly predict institutionalization either during the 10- or 18-year follow-ups.
conclusionsA practical index based on routine laboratory tests can be used to predict mortality among older people. An LI could be automatically counted from routine laboratory results and thus an easily applicable screening instrument in clinical settings.
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