ArticleBMC genomics2021
Genomic insight into diet adaptation in the biological control agent Cryptolaemus montrouzieri.
Article in BMC genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Comparative genomic analysis reveals the genetic basis of the environmental adaptability of Propylea japonica.BMC genomics · 2025Article
- Modeling the Effect of the Biological Control ofPlants (Basel, Switzerland) · 2025Article
- Alternative splicing fine-tunes prey shift of Coccinellini lady beetles to non-target insect.BMC genomics · 2025Article
- Molecular evolution of dietary shifts in ladybird beetles (Coleoptera: Coccinellidae): from fungivory to carnivory and herbivory.BMC biology · 2025Article
- Alternative splicing perspective to prey preference of environmentally friendly biological agent Cryptolaemus montrouzieri.BMC genomics · 2024Article
- PhyloAln: A Convenient Reference-Based Tool to Align Sequences and High-Throughput Reads for Phylogeny and Evolution in the Omic Era.Molecular biology and evolution · 2024Article
- Effect ofInsects · 2024Article
- The chromosome-level genome assembly of the giant dobsonfly Acanthacorydalis orientalis (McLachlan, 1899).Scientific data · 2024Article
- Differential Proteomics Analysis Unraveled Mechanisms ofInsects · 2022Article
- Article
- Genomic insight into the scale specialization of the biological control agent Novius pumilus (Weise, 1892).BMC genomics · 2022Article
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Authors and funding
8 authors.
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Abstract
backgroundThe ladybird beetle Cryptolaemus montrouzieri Mulsant, 1853 (Coleoptera, Coccinellidae) is used worldwide as a biological control agent. It is a predator of various mealybug pests, but it also feeds on alternative prey and can be reared on artificial diets. Relatively little is known about the underlying genetic adaptations of its feeding habits.
resultsWe report the first high-quality genome sequence for C. montrouzieri. We found that the gene families encoding chemosensors and digestive and detoxifying enzymes among others were significantly expanded or contracted in C. montrouzieri in comparison to published genomes of other beetles. Comparisons of diet-specific larval development, survival and transcriptome profiling demonstrated that differentially expressed genes on unnatural diets as compared to natural prey were enriched in pathways of nutrient metabolism, indicating that the lower performance on the tested diets was caused by nutritional deficiencies. Remarkably, the C. montrouzieri genome also showed a significant expansion in an immune effector gene family. Some of the immune effector genes were dramatically downregulated when larvae were fed unnatural diets.
conclusionWe suggest that the evolution of genes related to chemosensing, digestion, and detoxification but also immunity might be associated with diet adaptation of an insect predator. These findings help explain why this predatory ladybird has become a successful biological control agent and will enable the optimization of its mass rearing and use in biological control programs.
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