Evidence map›Paper›PMID 33631544›Full record

ArticleDrug and alcohol dependence2021

Patterns of clinic switching and continuity of medication for opioid use disorder in a Medicaid-enrolled population.

Evan S Cole, Coleman Drake, Ellen DiDomenico, Michael Sharbaugh, Joo Yeon Kim, Dylan Nagy, Gerald Cochran, Adam J Gordon, Walid F Gellad, Janice Pringle and 5 more

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Evan S ColeUniversity of Pittsburgh Graduate School of Public Health, Department of Health Policy and Management, 130 DeSoto Street, Pittsburgh, PA, 15261, United States. Electronic address: evancole@pitt.edu.
Coleman DrakeUniversity of Pittsburgh Graduate School of Public Health, Department of Health Policy and Management, 130 DeSoto Street, Pittsburgh, PA, 15261, United States.
Ellen DiDomenicoPennsylvania Department of Drug and Alcohol Programs 2601 N 3rd St, Harrisburg, PA, 17110, United States.
Michael SharbaughUniversity of Pittsburgh Graduate School of Public Health, Department of Health Policy and Management, 130 DeSoto Street, Pittsburgh, PA, 15261, United States.
Joo Yeon KimUniversity of Pittsburgh Graduate School of Public Health, Department of Health Policy and Management, 130 DeSoto Street, Pittsburgh, PA, 15261, United States.
Dylan NagyUniversity of Pittsburgh Graduate School of Public Health, Department of Health Policy and Management, 130 DeSoto Street, Pittsburgh, PA, 15261, United States.
Gerald CochranUniversity of Utah School of Medicine, Department of Internal Medicine, Division of Epidemiology, 295 Chipeta Way, Salt Lake City, UT, 84132, United States.
Adam J GordonUniversity of Utah School of Medicine, Department of Internal Medicine, Division of Epidemiology, 295 Chipeta Way, Salt Lake City, UT, 84132, United States.
Walid F GelladUniversity of Pittsburgh Graduate School of Public Health, Department of Health Policy and Management, 130 DeSoto Street, Pittsburgh, PA, 15261, United States; University of Pittsburgh School of Medicine, Division of General Internal Medicine, UPMC Montefiore Hospital, Suite W933, Pittsburgh, PA, 15213, United States.
Janice PringleUniversity of Pittsburgh School of Pharmacy, Program Evaluation and Research Unit 5607 Baum Blvd, Pittsburgh, PA, 15206, United States.
Jack WarwickUniversity of Pittsburgh School of Pharmacy, Program Evaluation and Research Unit 5607 Baum Blvd, Pittsburgh, PA, 15206, United States.
Chung-Chou H ChangUniversity of Pittsburgh School of Medicine, Division of General Internal Medicine, UPMC Montefiore Hospital, Suite W933, Pittsburgh, PA, 15213, United States.
Julie KmiecUniversity of Pittsburgh, Department of Psychiatry, Thomas Detre Hall, 3811 O'Hara Street, Pittsburgh, PA, 15213, United States.
David KelleyPennsylvania Department of Human Services, 625 Forster St, Harrisburg, PA, 17120, United States.
Julie M DonohueUniversity of Pittsburgh Graduate School of Public Health, Department of Health Policy and Management, 130 DeSoto Street, Pittsburgh, PA, 15261, United States.

Funding

Geographic Access to Medication Assisted Treatment for Medicaid Enrollees with Opioid Use DisorderK01DA051761 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DRAKE, COLEMAN · 2020 to 2023
$692k
AHRQ HHS R18 HS025072NIDA NIH HHS K01 DA051761
6 · The paper itself

Abstract

backgroundMany persons with opioid use disorder (OUD) initiate medication for opioid use disorder (MOUD) with one clinic and switch to another clinic during their course of treatment. These switches may occur for referrals or for unplanned reasons. It is unknown, however, what effect switching MOUD clinics has on continuity of MOUD treatment or on overdoses.

objectiveTo examine patterns of switching MOUD clinics and its association with the proportion of days covered (PDC) by MOUD, and opioid-related overdose.

designCross-sectional retrospective analysis of Pennsylvania Medicaid claims data. MAIN MEASURES: MOUD clinic switches (i.e., filling a MOUD prescription from a prescriber located in a different clinic than the previous prescriber), PDC, and opioid-related overdose.

resultsAmong 14,107 enrollees, 43.2 % switched clinics for MOUD at least once during the 270 day period. In multivariate regression results, enrollees who were Non-Hispanic black (IRR = 1.43; 95 % CI = 1.24-1.65; p < 0.001), had previous methadone use (IRR = 1.32; 95 % CI = 1.13-1.55; p < 0.001), and a higher total number of office visits (IRR = 1.01; CI = 1.01-1.01; p < 0.001) had more switches. The number of clinic switches was positively associated with PDC (OR = 1.12; 95 % CI = 1.10-1.13). In secondary analyses, we found that switches for only one MOUD fill were associated with lower PDC (OR = 0.97; 95 % CI = 0.95-0.99), while switches for more than one MOUD fill were associated with higher PDC (OR = 1.40; 95 % CI = 1.36-1.44). We did not observe a relationship between opioid-related overdose and clinic switches.

conclusionsLack of prescriber continuity for receiving MOUD may not be problematic as it is for other conditions, insofar as it is related to overdose and PDC.

Indexed as

AdolescentAdultAmbulatory CareAmbulatory Care FacilitiesAnalgesics, OpioidContinuity of Patient CareCross-Sectional StudiesDrug PrescriptionsFemaleHumansMaleMedicaidMiddle AgedOpiate OverdoseOpioid-Related DisordersPennsylvaniaAnalgesics, OpioidContinuityMedications for opioid use disorderOpioid use disorder

Identifiers

PMID33631544
PMCPMC8931627

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.