Evidence map›Paper›PMID 33631469›Full record

ArticleNeurobiology of aging2021

Imaging tau burden in dementia with Lewy bodies using [

Elijah Mak, Nicolas Nicastro, Maura Malpetti, George Savulich, Ajenthan Surendranathan, Negin Holland, Luca Passamonti, P Simon Jones, Stephen F Carter, Li Su and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Neurobiology of aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Sex differences inFrontiers in dementia · 2025
    Pooled it
  3. Pooled it
  4. Gray Matter Microstructure Measured Using Diffusion Imaging as a Biomarker of Severity in Lewy Body Diseases.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  5. Neuropathological correlates of imaging in dementia with Lewy bodies.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Visual reading for [Frontiers in neuroscience · 2023
    Article
  17. Dementia with Lewy bodies: Impact of co-pathologies and implications for clinical trial design.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Review
  18. Article
  19. Have (R)-[European journal of nuclear medicine and molecular imaging · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 4 countries.

Elijah MakDepartment of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Nicolas NicastroDepartment of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK; Department of Clinical Neurosciences, Geneva University Hospitals, Geneva, Switzerland.
Maura MalpettiDepartment of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
George SavulichDepartment of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Ajenthan SurendranathanDepartment of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Negin HollandDepartment of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Luca PassamontiDepartment of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
P Simon JonesDepartment of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Stephen F CarterDepartment of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Li SuDepartment of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Young T HongDepartment of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK; Wolfson Brain Imaging Centre, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Tim D FryerDepartment of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK; Wolfson Brain Imaging Centre, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Guy B WilliamsDepartment of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK; Wolfson Brain Imaging Centre, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Franklin AigbirhioDepartment of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
James B RoweDepartment of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
John T O'BrienDepartment of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK. Electronic address: john.obrien@medschl.cam.ac.uk.
University of Cambridge · GB

Funding

Department of Health SUAG/004 RG91365Medical Research Council MC_U105597119Medical Research Council MC_UU_00005/12Medical Research Council MR/K02308X/1Medical Research Council MR/M009041/1Medical Research Council MR/M024873/1Medical Research Council MR/P01271X/1Wellcome TrustWellcome Trust 103838
6 · The paper itself

Abstract

Alzheimer's disease (AD) pathology is frequently observed as a comorbidity in people with dementia with Lewy bodies (DLB). Here, we evaluated the in vivo distribution of tau burden and its influence on the clinical phenotype of DLB. Tau deposition was quantified using [

Indexed as

AgedAged, 80 and overCarbolinesFemaleFluorine RadioisotopesHumansInflammationLewy Body DiseaseMaleMicrogliaMiddle AgedPhenotypePositron-Emission TomographyRadioisotopesRadiopharmaceuticalsSeverity of Illness Index7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indoleCarbolinesFluorine-18Fluorine RadioisotopesRadioisotopesRadiopharmaceuticalstau ProteinsAmyloidDementiaLewy bodiesNeuroinflammationTau

Identifiers

PMID33631469
PMCPMC8209140
OpenAlexW3105007744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.