ArticlePediatric pulmonology2021
Comparison of chest radiography and chest CT for evaluation of pediatric COVID-19 pneumonia: Does CT add diagnostic value?
Article in Pediatric pulmonology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 24 citations in OpenAlex.
- Machine learning models for the prediction of preclinical coal workers' pneumoconiosis: integrating CT radiomics and occupational health surveillance records.Journal of translational medicine · 2025Article
- Unusual pediatric lung infections: imaging findings.Pediatric radiology · 2024Review
- Radiographic patterns and severity scoring of COVID-19 pneumonia in children: a retrospective study.BMC medical imaging · 2023Article
- Covid-19 omicron variant infection in neonates of Guangdong province-a report of 52 cases.Frontiers in pediatrics · 2023Article
- Clinical and radiological characteristics of pediatric COVID-19 before and after the Omicron outbreak: a multi-center study.Frontiers in pediatrics · 2023Article
- Imaging findings in acute pediatric coronavirus disease 2019 (COVID-19) pneumonia and multisystem inflammatory syndrome in children (MIS-C).Pediatric radiology · 2022Review
- Impact of X-radiation in the management of COVID-19 disease.World journal of radiology · 2022Review
- COVID-19 Detection in CT/X-ray Imagery Using Vision Transformers.Journal of personalized medicine · 2022Article
- COVID-19 Infection in Children: Diagnosis and Management.Current infectious disease reports · 2022Review
- Computed tomography findings in 3,557 COVID-19 infected children: a systematic review.Quantitative imaging in medicine and surgery · 2021Review
- Serum biochemical parameters as a surrogate marker for chest computed tomography in children with COVID-19.Future virology · 2021Article
- Comparison of chest radiography and chest CT for evaluation of pediatric COVID-19 pneumonia: Does CT add diagnostic value?Pediatric pulmonology · 2021Article
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Authors and funding
11 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFirst, to investigate the added diagnostic value of chest computed tomography (CT) for evaluating COVID-19 in symptomatic children by comparing chest CT findings with chest radiographic findings, and second, to identify the imaging signs and patterns on CT associated with COVID-19 pneumonia in children. MATERIALS AND
methodsFrom March 2020 to December 2020, 56 consecutive children (33 males and 23 girls; mean age ± SD, 14.8 ± 5.0 years; range, 9 months-18 years) with mild to moderate symptom and laboratory confirmed COVID-19 (based on Centers for Disease Control criteria) underwent both chest radiography and chest CT on the same day within the first 2 days of initial presentation to the hospital. Two experienced radiologists independently evaluated chest radiographs and chest CT studies for thoracic abnormalities. The findings from chest radiography and chest CT were compared to evaluate the added diagnostic value of chest CT for affecting patient management. Interobserver agreement was measured with Cohen's κ statistics.
resultsEleven (19.6%) of 56 patients had abnormal chest radiographic findings, including ground-glass opacity (GGO) in 5/11 (45.4%) and combined GGO and consolidation in 6/11 (54.5%). On chest CT, 26 (46.4%) of 56 patients had abnormal CT findings, including combined GGO and consolidation in 19/26 (73.1%), GGO in 6/26 (23.1%), and consolidation in 1/26 (3.8%). Chest CT detected all thoracic abnormalities seen on chest radiography in 11/26 (42.3%) cases. In 15/26 (57.7%), chest CT detected lung abnormalities that were not observed on chest radiography, which included GGO and consolidation in 9/15 (60%), GGO in 5/15 (33.3%), and consolidation in 1/15 (6.6%) cases. These additional CT findings did not affect patient management. In addition, chest CT detected radiological signs and patterns, including the halo sign, reversed halo sign, crazy paving pattern, and tree-in-bud pattern. There was almost perfect interobserver agreement between the two reviewers for detecting findings on both chest radiographs (κ, 0.89, p = .001) and chest CT (κ, 0.96, p = .001) studies.
conclusionChest CT detected lung abnormalities, including GGO and/or consolidation, that were not observed on chest radiography in more than half of symptomatic pediatric patients with COVID-19 pneumonia. However, these additional CT findings did not affect patient management. Therefore, CT is not clinically indicated for the initial evaluation of mild to moderately symptomatic pediatric patients with COVID-19 pneumonia.
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