Evidence map›Paper›PMID 33630715›Full record

ArticleThe Journal of international medical research2021

Sudden sensorineural hearing loss during pregnancy: etiology, treatment, and outcome.

Yi Qian, Houyong Kang, Guohua Hu, Shixun Zhong, Wenqi Zuo, Yan Lei, Zhengyan Xu, Tao Chen, Jihong Zeng

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Pathophysiologic phenotyping of idiopathic sudden sensorineural hearing loss: toward precision management.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yi QianDepartment of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing City, China.ORCID https://orcid.org/0000-0001-5549-6291
Houyong KangDepartment of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing City, China.
Guohua HuDepartment of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing City, China.
Shixun ZhongDepartment of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing City, China.
Wenqi ZuoDepartment of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing City, China.
Yan LeiDepartment of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing City, China.
Zhengyan XuDepartment of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing City, China.
Tao ChenDepartment of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing City, China.
Jihong ZengDepartment of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing City, China.
The Affiliated Yongchuan Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the etiologies, treatments, and outcomes of sensorineural hearing loss (SSNHL) during pregnancy. STUDY

designRetrospective chart review of 25 pregnant patients treated for SSNHL between January 2012 and September 2019. Forty-nine age matched non-pregnant women with severe and profound hearing loss diagnosed with SSNHL during the same period served as controls. Data were recorded on age, symptoms, onset of hearing loss, audiometric results, treatments, and outcomes.

resultsThe mean age was 29.6 years (range 23-38 years). Intratympanic steroids (ITS) were administered in 15 (60.0%) pregnant women with SSNHL. Three women were treated with postauricular steroids only, while another woman was treated with intravenous ginkgo leaf extract and dipyridamole. The remaining six women received no medications. More than half (8/15, 53.3%) of pregnant women with SSNHL receiving ITS experienced hearing improvement. Pregnant women with profound hearing loss who received no medication had no hearing improvement. Most pregnant women with SSNHL (12/15, 80.0%) had higher fibrinogen levels than controls (mean values 3.77±0.71 g/L and 2.54±0.48 g/L, respectively).

conclusionFibrinogen could be a risk factor for SSNHL during pregnancy. ITS may benefit pregnant women with severe and profound SSNHL.

Indexed as

Hearing Loss, SensorineuralHearing Loss, SuddenAdultAudiometryFemaleHumansInjection, IntratympanicPregnancyRetrospective StudiesTreatment OutcomeYoung Adultdrug therapyfibrinogenintratympanic steroidsPregnancyretrospective analysissudden sensorineural hearing loss

Identifiers

PMID33630715
PMCPMC7925942
OpenAlexW3131129310

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.