Evidence map›Paper›PMID 33630616›Full record

ArticleBehavioral neuroscience2021

Amygdala central nucleus modulation of cerebellar learning in female rats.

John H Freeman, Sean J Farley, Samantha R Pierson

Abstract read
In one paragraph

Article in Behavioral neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

John H FreemanDepartment of Psychological and Brain Sciences, University of Iowa.ORCID 0000-0002-3199-9182
Sean J FarleyDepartment of Psychological and Brain Sciences, University of Iowa.ORCID 0000-0001-6232-5423
Samantha R PiersonDepartment of Psychological and Brain Sciences, University of Iowa.ORCID 0000-0002-8376-4465

Funding

Cerebellar Interactions with the Amygdala and Prefrontal Cortex during LearningR01NS088567 · NINDS · UNIVERSITY OF IOWA · PI FREEMAN, JOHN H · 2015 to 2024
$3.5M
NINDS NIH HHS R01 NS088567
6 · The paper itself

Abstract

Previous studies found that inactivation of the central amygdala (CeA) severely impaired acquisition of cerebellum-dependent delay eye-blink conditioning (EBC) in male rats and rabbits. Sex differences in EBC and the effects of stress on EBC have been reported and might be related to sex differences in amygdala modulation of cerebellar learning. The current study examined the effects of CeA inactivation with muscimol on acquisition and retention of EBC in female rats. Like male rats, CeA inactivation in female rats severely impaired EBC acquisition and retention. Comparison of the female data with previously published data from males indicates no substantive sex differences in the effects of CeA inactivation on acquisition or retention of EBC. The results indicate that amygdala modulation of cerebellar learning is not sex-specific. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Indexed as

Central Amygdaloid NucleusConditioning, EyelidAnimalsCerebellumFemaleMaleMuscimolRabbitsRatsRats, Long-EvansMuscimol

Identifiers

PMID33630616
PMCPMC8282618

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.