Evidence map›Paper›PMID 33630589›Full record

ArticleACS nano2021

Biodegradable Harmonophores for Targeted High-Resolution

Ali Yasin Sonay, Konstantinos Kalyviotis, Sine Yaganoglu, Aysen Unsal, Martina Konantz, Claire Teulon, Ingo Lieberwirth, Sandro Sieber, Shuai Jiang, Shahed Behzadi and 5 more

Open access · hybridAbstract read
In one paragraph

Article in ACS nano, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

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  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Ali Yasin SonayDepartment of Biosystems Science and Engineering (D-BSSE), Eidgenössische Technische Hochschule (ETH) Zurich, 4058 Basel, Switzerland.
Konstantinos KalyviotisDepartment of Bioengineering, Imperial College London, South Kensington Campus, London SW7 2AZ, U.K.
Sine YaganogluDepartment of Biosystems Science and Engineering (D-BSSE), Eidgenössische Technische Hochschule (ETH) Zurich, 4058 Basel, Switzerland.
Aysen UnsalDepartment of Bioengineering, Imperial College London, South Kensington Campus, London SW7 2AZ, U.K.
Martina KonantzDepartment of Biomedicine, University Hospital Basel and University of Basel, 4031 Basel, Switzerland.
Claire TeulonLaboratory for Fundamental BioPhotonics, Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
Ingo LieberwirthMax Planck Institute for Polymer Research, 55128 Mainz, Germany.ORCID 0000-0003-1323-524X
Sandro SieberDivision of Pharmaceutical Technology, Department of Pharmaceutical Sciences, University of Basel, 4031 Basel, Switzerland.
Shuai JiangMax Planck Institute for Polymer Research, 55128 Mainz, Germany.ORCID 0000-0002-8639-3495
Shahed BehzadiMax Planck Institute for Polymer Research, 55128 Mainz, Germany.
Daniel CrespyMax Planck Institute for Polymer Research, 55128 Mainz, Germany.
Katharina LandfesterMax Planck Institute for Polymer Research, 55128 Mainz, Germany.
Sylvie RokeLaboratory for Fundamental BioPhotonics, Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.ORCID 0000-0002-6062-7871
Claudia LengerkeDepartment of Biomedicine, University Hospital Basel and University of Basel, 4031 Basel, Switzerland.
Periklis PantazisDepartment of Biosystems Science and Engineering (D-BSSE), Eidgenössische Technische Hochschule (ETH) Zurich, 4058 Basel, Switzerland.ORCID 0000-0002-8367-9332
Max Planck Institute for Polymer Research · DEBoard of the Swiss Federal Institutes of Technology · CHUniversity of Basel · CHÉcole Polytechnique Fédérale de Lausanne · CHImperial College London · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Optical imaging probes have played a major role in detecting and monitoring a variety of diseases. In particular, nonlinear optical imaging probes, such as second harmonic generating (SHG) nanoprobes, hold great promise as clinical contrast agents, as they can be imaged with little background signal and unmatched long-term photostability. As their chemical composition often includes transition metals, the use of inorganic SHG nanoprobes can raise long-term health concerns. Ideally, contrast agents for biomedical applications should be degraded

Indexed as

Molecular ImagingZebrafishAnimalsMicroscopy, FluorescencePeptidesPeptidesbiodegradableferroelectricimagingsecond harmonic generationself-assembly

Identifiers

PMID33630589
PMCPMC8023799
OpenAlexW3130867110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.