Evidence map›Paper›PMID 33630406›Full record

ArticleESC heart failure2021

Simple equations to predict the effects of veno-venous ECMO in decompensated Eisenmenger syndrome.

Jean Bonnemain, Denise Auberson, Tobias Rutz, Patrick Yerly, John-David Aubert, Aurélien Roumy, Olivier Pantet, Marco Rusca, Lucas Liaudet, Lise Piquilloud

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Jean BonnemainThe Service of Adult Intensive Care Medicine, University Hospital and Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 46, Lausanne, CH-1011, Switzerland.
Denise AubersonThe Service of Cardiology, University Hospital and Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 46, Lausanne, CH-1011, Switzerland.
Tobias RutzThe Service of Cardiology, University Hospital and Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 46, Lausanne, CH-1011, Switzerland.
Patrick YerlyThe Service of Cardiology, University Hospital and Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 46, Lausanne, CH-1011, Switzerland.
John-David AubertThe Service of Pneumology, University Hospital and Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 46, Lausanne, CH-1011, Switzerland.
Aurélien RoumyThe Service of Cardiac Surgery, University Hospital and Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 46, Lausanne, CH-1011, Switzerland.
Olivier PantetThe Service of Adult Intensive Care Medicine, University Hospital and Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 46, Lausanne, CH-1011, Switzerland.
Marco RuscaThe Service of Adult Intensive Care Medicine, University Hospital and Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 46, Lausanne, CH-1011, Switzerland.
Lucas LiaudetThe Service of Adult Intensive Care Medicine, University Hospital and Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 46, Lausanne, CH-1011, Switzerland.
Lise PiquilloudThe Service of Adult Intensive Care Medicine, University Hospital and Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 46, Lausanne, CH-1011, Switzerland.
University of Lausanne · CHEquilibrium Research · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult patients with uncorrected congenital heart diseases and chronic intracardiac shunt may develop Eisenmenger syndrome (ES) due to progressive increase of pulmonary vascular resistance, with significant morbidity and mortality. Acute decompensation of ES in conditions promoting a further increase of pulmonary vascular resistance, such as pulmonary embolism or pneumonia, can precipitate major arterial hypoxia and death. In such conditions, increasing systemic oxygenation with veno-venous extracorporeal membrane oxygenation (VV-ECMO) could be life-saving, serving as a bridge to treat a potential reversible cause for the decompensation, or to urgent lung transplantation. Anticipating the effects of VV-ECMO in this setting could ease the clinical decision to initiate such therapeutic strategy. Here, we present a series of equations to accurately predict the effects of VV-ECMO on arterial oxygenation in ES and illustrate this point by a case of ES decompensation with refractory hypoxaemia consecutive to an acute respiratory failure due to viral pneumonia.

Indexed as

Eisenmenger ComplexExtracorporeal Membrane OxygenationPneumonia, ViralRespiratory Distress SyndromeAdultHumansECMOEisenmenger syndromeExtracorporeal membrane oxygenationHypoxaemiaVeno-venous

Identifiers

PMID33630406
PMCPMC8006687
OpenAlexW3131993519

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.