Evidence map›Paper›PMID 33630172›Full record

ReviewCurrent pain and headache reports2021

A Comprehensive Update of the Superior Hypogastric Block for the Management of Chronic Pelvic Pain.

Ivan Urits, Ruben Schwartz, Jared Herman, Amnon A Berger, David Lee, Christopher Lee, Alec M Zamarripa, Annabel Slovek, Kelly Habib, Laxmaiah Manchikanti and 2 more

2 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06204874 narecruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of Pulsed Radiofrequency Ablation of the Superior Hypogastric Plexus for Treatment of Bladder Pain Syndrome: A Case Series

TypeinterventionalSponsorWalter Reed National Military Medical CenterRan2024 to 2026Enrolled5ConditionsBladder Pain SyndromeArmsPulsed radiofrequency ablation
NCT07388953 narecruitingnot on this mapstarted 2026, after this paper: background citation

Peripheral Autonomic Block (BAP) Plus Transversus Abdominis Plane Block (TAP) for Postoperative Analgesia After Minimally Invasive Left-Sided Colorectal Resection (BAPTAP): A Randomized, Controlled, Double-Blind Trial

TypeinterventionalSponsorFaculdade de Ciências Médicas de Minas GeraisRan2026 to 2027Enrolled140ConditionsColorectal Cancer, Colorectal Surgery, Anesthesia, Autonomic Nerve BlockArmsMinimally Invasive Left-Sided Colorectal Resection, BAPTAP (Peripheral Autonomic Blockade + TAP Block), Trocar/Incision Infiltration
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Phenol Neurolysis in Pain and Palliative Medicine.Pain practice : the official journal of World Institute of Pain · 2026
    Review
  3. Article
  4. Observational
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Agents Used for Nerve Blocks and Neurolysis.Seminars in interventional radiology · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. A Pain Desensitization Algorithm for Phenotyping and Treating Chronic Pelvic Pain.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Ivan UritsBeth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care, and Pain Medicine, Harvard Medical School, Boston, MA, USA.
Ruben SchwartzDepartment of Anesthesiology, Mount Sinai Medical Center, Miami Beach, FL, USA. rubenschwartz@yahoo.com.ORCID http://orcid.org/0000-0003-1571-800X
Jared HermanDepartment of Anesthesiology, Mount Sinai Medical Center, Miami Beach, FL, USA.
Amnon A BergerBeth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care, and Pain Medicine, Harvard Medical School, Boston, MA, USA.
David LeeDepartment of Anesthesiology, University of Arizona College of Medicine - Phoenix, Phoenix, AZ, USA.
Christopher LeeCreighton University School of Medicine - Phoenix Regional Campus, Phoenix, AZ, USA.
Alec M ZamarripaDepartment of Anesthesiology, University of Arizona College of Medicine - Phoenix, Phoenix, AZ, USA.
Annabel SlovekValley Pain Consultants - Envision Physician Services, Phoenix, AZ, USA.
Kelly HabibDepartment of Anesthesiology, University of Arizona College of Medicine - Phoenix, Phoenix, AZ, USA.
Laxmaiah ManchikantiPain Management Centers of America, Paducah, KY, USA.
Alan D KayeDepartment of Anesthesiology, Louisiana State University Shreveport, Shreveport, LA, USA.
Omar ViswanathDepartment of Anesthesiology, Louisiana State University Shreveport, Shreveport, LA, USA.
University of Arizona · USBeth Israel Deaconess Medical Center · USCreighton University · USMount Sinai Medical Center · USLouisiana State University in Shreveport · USPain Management Centers Of America · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis is a comprehensive review of the superior hypogastric block for the management of chronic pelvic pain. It reviews the background, including etiology, epidemiology, and current treatment available for chronic pelvic pain. It then presents the superior hypogastric block and reviews the seminal and most recent evidence about its use in chronic pelvic pain. RECENT

findingsSeveral definitions exist for chronic pelvic pain (CPP), making the diagnosis more challenging for the clinician; however, they commonly describe continuous pain lasting 6 months in the pelvis, with an overwhelming majority of patients being reproductive-aged women. This pain is often one of mechanical, inflammatory, or neuropathic. It is generally underdiagnosed and affects anywhere between 5 and 26% of women. The diagnosis of chronic pelvic pain is clinical, consisting of mainly of a thorough history and physical and ruling out other causes. The pathophysiology is often endometriosis (70%) and also includes PID, adhesions, adenomyosis, uterine fibroids, chronic processes of the GI and urinary tracts, as well as pelvic-intrinsic musculoskeletal causes. Treatment includes physical therapy, cognitive behavioral therapy, and oral and parenteral opioids. Interventional techniques provide an added tier of treatment and may help to reduce the requirement for chronic opioid use. Superior hypogastric plexus block is one of the available interventional techniques; first described in 1990, it has been shown to provide long-lasting relief in 50-70% of patients who underwent the procedure. Two approaches described so far, both under fluoroscopy, have seen similar results. More recently, ultrasound and CT-guided procedures have also been described with similar success. The injectate includes local anesthetic, steroids, and neurolytic agents such as phenol or ethanol. CPP is a common debilitating condition. It is diagnosed clinically and is underdiagnosed globally. Current treatments can be helpful at times but may fall short of satisfactory pain relief. Interventional techniques provide an added layer of treatment as well as reduce the requirement for opioids. Superior hypogastric plexus block provides long-lasting relief in many patients, regardless of approach. Evidence level is limited, and further RCTs could help provide better tools for evaluation and patient selection.

Indexed as

Analgesics, OpioidAnesthetics, LocalAutonomic Nerve BlockChronic PainEndometriosisFemaleHumansHypogastric PlexusInflammation MediatorsPain ManagementPain MeasurementPelvic PainAnalgesics, OpioidAnesthetics, LocalInflammation MediatorsChronic painEndometriosisInjectional pain therapyNerve blockNeurolysisPID

Identifiers

PMID33630172
OpenAlexW3130659571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.