Evidence map›Paper›PMID 33629952›Full record

ArticleeLife2021

Identification of host proteins differentially associated with HIV-1 RNA splice variants.

Rachel Knoener, Edward Evans, Jordan T Becker, Mark Scalf, Bayleigh Benner, Nathan M Sherer, Lloyd M Smith

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  4. HIV-1 Vif and Vpr cooperatively modulate the cell cycle to maximize per-cell virion production.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Rachel KnoenerDepartment of Chemistry, University of Wisconsin, Madison, United States.ORCID 0000-0002-2787-1098
Edward EvansMcArdle Laboratory for Cancer Research and Institute for Molecular Virology, University of Wisconsin, Madison, United States.
Jordan T BeckerMcArdle Laboratory for Cancer Research and Institute for Molecular Virology, University of Wisconsin, Madison, United States.ORCID 0000-0002-0239-5443
Mark ScalfDepartment of Chemistry, University of Wisconsin, Madison, United States.
Bayleigh BennerMcArdle Laboratory for Cancer Research and Institute for Molecular Virology, University of Wisconsin, Madison, United States.ORCID 0000-0002-6266-5740
Nathan M ShererMcArdle Laboratory for Cancer Research and Institute for Molecular Virology, University of Wisconsin, Madison, United States.ORCID 0000-0001-9974-236X
Lloyd M SmithDepartment of Chemistry, University of Wisconsin, Madison, United States.ORCID 0000-0002-6652-8639
University of Wisconsin–Madison · US

Funding

BIOTECHNOLOGY TRAINING PROGRAMT32GM008349 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI FOX, BRIAN G · 1989 to 2019
$22.5M
The Center for HIV RNA Studies (CRNA)U54AI150470 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TELESNITSKY, ALICE · 2019 to 2021
$15.1M
Training in Cancer Biology Training GrantT32CA009135 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI SUGDEN, WILLIAM M. · 1985 to 2024
$10.4M
The Cell Biology of HIV-1 Genome TraffickingR01AI110221 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI Nathan M Sherer · 2014 to 2026
$4.4M
Sequence-specific Hybridization Capture to Reveal the lncRNA Interactome in Prostate CancerR01CA193481 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI DAVID F. JARRARD, Lloyd M Smith · 2015 to 2026
$3.4M
NCI NIH HHS R01 CA193481NCI NIH HHS T32 CA009135NIAID NIH HHS R01 AI110221NIAID NIH HHS U54 AI150470NIGMS NIH HHS T32 GM008349
6 · The paper itself

Abstract

HIV-1 generates unspliced (US), partially spliced (PS), and completely spliced (CS) classes of RNAs, each playing distinct roles in viral replication. Elucidating their host protein 'interactomes' is crucial to understanding virus-host interplay. Here, we present HyPR-MS

Indexed as

RNA SplicingVirus ReplicationHIV-1Host-Pathogen InteractionsHumansRNA, ViralRNA, Viralbiochemistrychemical biologyHIVhumaninteractomeproteomicsRNA binding proteinsRNA imagingsplicingvirus

Identifiers

PMID33629952
PMCPMC7906601
OpenAlexW3130333980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.