Evidence map›Paper›PMID 33629950›Full record

SynthesisHealth technology assessment (Winchester, England)2021

Cognitive-behavioural therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis.

Beth Fordham, Thavapriya Sugavanam, Katherine Edwards, Karla Hemming, Jeremy Howick, Bethan Copsey, Hopin Lee, Milla Kaidesoja, Shona Kirtley, Sally Hopewell and 6 more

Open access · diamondAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Health technology assessment (Winchester, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Cognitive behavioural therapy (group) for schizophrenia.The Cochrane database of systematic reviews · 2022
    Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Article
  11. Review
  12. Article
  13. Review
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  15. Article
  16. Treating persistent pain after breast cancer: practice gaps and future directions.Journal of cancer survivorship : research and practice · 2023
    Article
  17. Article
  18. Evaluation and Medical Management of Chronic Pelvic Pain.Seminars in interventional radiology · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 3 countries.

Beth FordhamNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.ORCID 0000-0001-5996-3563
Thavapriya SugavanamNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-3033-2028
Katherine EdwardsNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-1092-0092
Karla HemmingInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.ORCID 0000-0002-2226-6550
Jeremy HowickFaculty of Philosophy, University of Oxford, Oxford, UK.ORCID 0000-0003-0280-7206
Bethan CopseyNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.ORCID 0000-0001-9783-6549
Hopin LeeNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.ORCID 0000-0001-5692-0314
Milla KaidesojaDepartment of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.ORCID 0000-0003-0372-8251
Shona KirtleyNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-7801-5777
Sally HopewellNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-6881-6984
Roshan das NairDepartment of Psychiatry and Applied Psychology, University of Nottingham, Nottingham, UK.ORCID 0000-0001-8143-7893
Robert HowardDivision of Psychiatry, University College London, London, UK.ORCID 0000-0002-3071-2338
Paul StallardDepartment for Health, University of Bath, Bath, UK.ORCID 0000-0001-8046-0784
Julia Hamer-HuntPublic and patient representative, Oxford, UK.
Zafra CooperDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0001-7963-656X
Sarah E LambNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.ORCID 0000-0003-4349-7195
Nuffield Orthopaedic Centre · GBUniversity College London · GBUniversity of Bath · GBUniversity of Birmingham · GBUniversity of Exeter · GBUniversity of Helsinki · FIUniversity of Nottingham · GBUniversity of Oxford · GBYale University · US

Funding

Cancer Research UK 27294Department of Health 15/174/24
6 · The paper itself

Abstract

backgroundCognitive-behavioural therapy aims to increase quality of life by changing cognitive and behavioural factors that maintain problematic symptoms. A previous overview of cognitive-behavioural therapy systematic reviews suggested that cognitive-behavioural therapy was effective for many conditions. However, few of the included reviews synthesised randomised controlled trials.

objectivesThis project was undertaken to map the quality and gaps in the cognitive-behavioural therapy systematic review of randomised controlled trial evidence base. Panoramic meta-analyses were also conducted to identify any across-condition general effects of cognitive-behavioural therapy. DATA SOURCES: The overview was designed with cognitive-behavioural therapy patients, clinicians and researchers. The Cochrane Library, MEDLINE, EMBASE, PsycINFO, Cumulative Index to Nursing and Allied Health Literature, Child Development & Adolescent Studies, Database of Abstracts of Reviews of Effects and OpenGrey databases were searched from 1992 to January 2019. REVIEW

methodsStudy inclusion criteria were as follows: (1) fulfil the Centre for Reviews and Dissemination criteria; (2) intervention reported as cognitive-behavioural therapy or including one cognitive and one behavioural element; (3) include a synthesis of cognitive-behavioural therapy trials; (4) include either health-related quality of life, depression, anxiety or pain outcome; and (5) available in English. Review quality was assessed with A MeaSurement Tool to Assess systematic Reviews (AMSTAR)-2. Reviews were quality assessed and data were extracted in duplicate by two independent researchers, and then mapped according to condition, population, context and quality. The effects from high-quality reviews were pooled within condition groups, using a random-effect panoramic meta-analysis. If the across-condition heterogeneity was

resultsA total of 494 reviews were mapped, representing 68% (27/40) of the categories of the LIMITATIONS: Data extraction and analysis were conducted at the review level, rather than returning to the individual trial data. This meant that the risk of bias of the individual trials could not be accounted for, but only the quality of the systematic reviews that synthesised them.

conclusionOwing to the consistency and homogeneity of the highest-quality evidence, it is proposed that cognitive-behavioural therapy can produce a modest general, across-condition benefit in health-related quality-of-life, anxiety and pain outcomes. FUTURE WORK: Future research should focus on how the modest effect sizes seen with cognitive-behavioural therapy can be increased, for example identifying alternative delivery formats to increase adherence and reduce dropout, and pursuing novel methods to assess intervention fidelity and quality. STUDY REGISTRATION: This study is registered as PROSPERO CRD42017078690.

fundingThis project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in

Indexed as

Cognitive Behavioral TherapyQuality of LifeAdolescentAgedAnxiety DisordersChildHumansSystematic Reviews as TopicTechnology Assessment, BiomedicalCOGNITIVE–BEHAVIOURAL THERAPYDATA ANALYSISINTERNATIONAL CLASSIFICATION OF DISEASESQUALITY OF LIFE

Identifiers

PMID33629950
PMCPMC7957459
OpenAlexW3129243236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.