Evidence map›Paper›PMID 33629608›Full record

ArticleThe Annals of otology, rhinology, and laryngology2021

Association of Social Determinants of Health with Time to Diagnosis and Treatment Outcomes in Idiopathic Subglottic Stenosis.

Jaclyn Lee, Li-Ching Huang, Lynn D Berry, Catherine Anderson, Milan R Amin, Michael S Benninger, Joel H Blumin, Jonathan M Bock, Paul C Bryson, Paul F Castellanos and 65 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Annals of otology, rhinology, and laryngology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

75 authors at 20 institutions in 4 countries.

Jaclyn LeeDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID https://orcid.org/0000-0001-9804-6995
Li-Ching HuangVanderbilt Center for Quantitative Sciences, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Lynn D BerryVanderbilt Center for Quantitative Sciences, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Catherine AndersonAustralian Market and Social Research Society, Glebe, NSW, Australia.
Milan R AminNYU Voice Center, Department of Otolaryngology-Head and Neck Surgery, New York University School of Medicine, New York, NY, USA.
Michael S BenningerDepartment of Otolaryngology-Head and Neck Surgery, Head and Neck Institute, Cleveland Clinic, Cleveland, OH, USA.
Joel H BluminDivision of Laryngology and Professional Voice, Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, WI, USA.
Jonathan M BockDivision of Laryngology and Professional Voice, Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID https://orcid.org/0000-0002-4367-7527
Paul C BrysonDepartment of Otolaryngology-Head and Neck Surgery, Head and Neck Institute, Cleveland Clinic, Cleveland, OH, USA.
Paul F CastellanosDivision of Otolaryngology, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
Sheau-Chiann ChenVanderbilt Center for Quantitative Sciences, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Matthew S ClaryDepartment of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine, Denver, CO, USA.
Seth M CohenDuke Voice Care Center, Division of Otolaryngology-Head and Neck Surgery, Duke University Medical Center, Durham, NC, USA.ORCID https://orcid.org/0000-0002-7965-604X
Brianna K CrawleyDepartment of Otolaryngology-Head and Neck Surgery, Loma Linda University Health, Loma Linda, CA, USA.
Seth H DaileyDepartment of Otolaryngology-Head and Neck Surgery, Loma Linda University Health, Loma Linda, CA, USA.ORCID https://orcid.org/0000-0002-3299-3014
James J DanieroDepartment of Otolaryngology-Head and Neck Surgery, University of Virginia Health System, Charlottesville, VA, USA.
Alessandro de AlarconDepartment of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA.
Donald T DonovanDepartment of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, TX, USA.
Eric S EdellDivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA.
Dale C EkbomDepartment of Otolaryngology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Daniel S FinkDepartment of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine, Denver, CO, USA.
Ramon A FrancoDepartment of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
C Gaelyn GarrettDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Elizabeth A GuardianiDepartment of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Alexander T HillelDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institution, Baltimore, MD, USA.
Henry T HoffmanDepartment of Otolaryngology-Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.ORCID https://orcid.org/0000-0003-4486-855X
Norman D HogikyanDepartment of Otolaryngology-Head and Neck Surgery, University of Michigan Medical Center, Ann Arbor, MI, USA.
Rebecca J HowellDepartment of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA.
Lena K HussainVanderbilt Center for Quantitative Sciences, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Michael M JohnsDepartment of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, CA, USA.
Jan L KasperbauerDepartment of Otolaryngology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Sid M KhoslaDepartment of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA.
Cheryl KinnardVanderbilt Center for Quantitative Sciences, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Robbi A KupferDepartment of Otolaryngology-Head and Neck Surgery, University of Michigan Medical Center, Ann Arbor, MI, USA.
Alexander J LangermanVanderbilt Center for Quantitative Sciences, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Robert J LentzVanderbilt Center for Quantitative Sciences, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Robert R LorenzDivision of Laryngology and Professional Voice, Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, WI, USA.
David G LottDepartment of Otorhinolaryngology, Mayo Clinic Scottsdale, Scottsdale, AZ, USA.ORCID https://orcid.org/0000-0001-6541-9687
Anne S LoweryDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Samir S MakaniDivision of Pulmonary and Critical Care Medicine, University of California, San Diego, San Diego, CA, USA.
Fabien MaldonadoDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Kyle MannionDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Laura MatrkaDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University Medical Center, Columbus, OH, USA.
Andrew J McWhorterDepartment of Otolaryngology, Louisiana State University Health Sciences Center-New Orleans, New Orleans, LA, USA.
Albert L MeratiDepartment of Otolaryngology-Head and Neck Surgery, University of Washington Medical Center, Seattle, WA, USA.
Matthew MoriDepartment of Otolaryngology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY USA.ORCID https://orcid.org/0000-0001-8743-5055
James L NettervilleDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Karla O'DellDepartment of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, CA, USA.
Julina OngkasuwanDepartment of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, TX, USA.ORCID https://orcid.org/0000-0001-8621-5456
Gregory N PostmaDepartment of Otolaryngology-Head and Neck Surgery, Medical College of Georgia at Augusta University, Augusta, GA, USA.
Lindsay S RederDepartment of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, CA, USA.
Sarah L RohdeDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Brent E RichardsonBastian Voice Institute, Downers Grove, IL, USA.ORCID https://orcid.org/0000-0001-5332-1930
Otis B RickmanDivision of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Clark A RosenDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, San Francisco, CA, USA.
Michael J RutterDepartment of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA.
Guri S SandhuNational Centre for Airway Reconstruction, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK.
Joshua S SchindlerDepartment of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University, Northwest Clinic for Voice and Swallowing, Portland, OR, USA.
G Todd SchneiderDepartment of Otolaryngology, University of Rochester, Rochester, NY, USA.
Rupali N ShahDepartment of Otolaryngology-Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Andrew G SikoraDepartment of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, TX, USA.
Robert J SinardDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Marshall E SmithDivision of Otolaryngology-Head and Neck Surgery, The University of Utah, Salt Lake City, UT, USA.
Libby J SmithDepartment of Otolaryngology-Head and Neck Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Ahmed M S SolimanDepartment of Otolaryngology-Head and Neck Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Sigríður SveinsdóttirLandspítali University Hospital, Reykjavik, Iceland.
Douglas J Van DaeleDepartment of Otolaryngology-Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
David VeiversDepartment of Otolaryngology-Head and Neck Surgery, Royal North Shore Hospital, Sydney, NSW, Australia.
Sunil P VermaDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, CA, USA.
Paul M WeinbergerDepartments of Otolaryngology, Molecular and Cellular Physiology, Feist-Weiller Cancer Center, LSU Shreveport, LA, USA.
Philip A WeissbrodDivision of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of California, San Diego, San Diego, CA, USA.
Christopher T WoottenDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Yu ShyrVanderbilt Center for Quantitative Sciences, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
David O FrancisDivision of Otolaryngology-Head and Neck Surgery, University of Wisconsin-Madison, Madison, WI, USA.
Alexander GelbardDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID https://orcid.org/0000-0003-0078-1305
Vanderbilt University Medical Center · USVanderbilt University · USUniversity of Cincinnati · USBaylor College of Medicine · USMayo Clinic · USMedical College of Wisconsin · USUniversity of Southern California · USCleveland Clinic · USLoma Linda University · USUniversity of California San Diego · USUniversity of Colorado Denver · USUniversity of Iowa Hospitals and Clinics · USUniversity of Michigan · USAugusta University · USBastian Voice Institute · USDuke Medical Center · USImperial College Healthcare NHS Trust · GBJohns Hopkins University · USLouisiana State University Health Sciences Center New Orleans · USLouisiana State University in Shreveport · US

Funding

Molecular Interrogation of the Host-Pathogen Interface in Idiopathic Subglottic StensosisR01HL146401 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GELBARD, ALEXANDER · 2019 to 2023
$1.9M
ECR Application: Unilateral Vocal Fold Paralysis-Related Disability Outcome: Development And ValidationR21DC016724 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI FRANCIS, DAVID O. · 2018 to 2019
$427k
NHLBI NIH HHS R01 HL146401NIDCD NIH HHS R21 DC016724
6 · The paper itself

Abstract

objectivesTo examine whether social determinants of health (SDH) factors are associated with time to diagnosis, treatment selection, and time to recurrent surgical intervention in idiopathic subglottic stenosis (iSGS) patients.

methodsAdult patients with diagnosed iSGS were recruited prospectively (2015-2017) via clinical providers as part of the North American Airway Collaborative (NoAAC) and via an online iSGS support community on Facebook. Patient-specific SDH factors included highest educational attainment (self-reported), median household income (matched from home zip code via U.S. Census data), and number of close friends (self-reported) as a measure of social support. Main outcomes of interest were time to disease diagnosis (years from symptom onset), treatment selection (endoscopic dilation [ED] vs cricotracheal resection [CTR] vs endoscopic resection with adjuvant medical therapy [ERMT]), and time to recurrent surgical intervention (number of days from initial surgical procedure) as a surrogate for disease recurrence.

resultsThe total 810 participants were 98.5% female, 97.2% Caucasian, and had a median age of 50 years (IQR, 43-58). The cohort had a median household income of $62 307 (IQR, $50 345-$79 773), a median of 7 close friends (IQR, 4-10), and 64.7% of patients completed college or graduate school. Education, income, and number of friends were not associated with time to diagnosis via multivariable linear regression modeling. Univariable multinominal logistic regression demonstrated an association between education and income for selecting ED versus ERMT, but no associations were noted for CTR. No associations were noted for time to recurrent surgical procedure via Kaplan Meier modeling and Cox proportional hazards regression.

conclusionsPatient education, income, and social support were not associated with time to diagnosis or time to disease recurrence. This suggests additional patient, procedure, or disease-specific factors contribute to the observed variations in iSGS surgical outcomes.

Indexed as

Social Determinants of HealthAdultFemaleFollow-Up StudiesHumansLaryngoscopyLaryngostenosisMaleMiddle AgedProspective StudiesRecurrenceTime FactorsTreatment OutcomeUnited StateseducationincomeiSGSsocial supportsurgical outcomestime to diagnosis

Identifiers

PMID33629608
PMCPMC8762607
OpenAlexW3131531210

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.