Evidence map›Paper›PMID 33629603›Full record

ReviewJournal of investigative medicine high impact case reports

Locus Minoris Resistentiae: Two Cases of Malignant Metastasis and Review of Literature.

Donya Farmand, Michael C Valdez, Leila Moosavi, Everardo Cobos

Open access · goldAbstract readReviewCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of investigative medicine high impact case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Beware ofInfection and drug resistance · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Donya FarmandDepartment of Medicine, Kern Medical-UCLA, Bakersfield, CA, USA.
Michael C ValdezDepartment of Medicine, Kern Medical-UCLA, Bakersfield, CA, USA.
Leila MoosaviDepartment of Medicine, Kern Medical-UCLA, Bakersfield, CA, USA.ORCID 0000-0001-8790-910X
Everardo CobosDepartment of Medicine, Kern Medical-UCLA, Bakersfield, CA, USA.
Kern Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Locus minoris resistentiae refers to a region of decreased resistance within the body. This occurs from changes to the microenvironment secondary to previous trauma and results in increased vulnerability. As a result, infection, inflammatory processes, and malignancy may localize to this area. In this article, we describe 2 unique cases of malignancy, primary prostate carcinoma and serous carcinoma of the ovary, both of which disseminated to sites of prior trauma. We review the available literature, discuss proposed pathophysiology, and highlight the need for further investigations along with increased clinician awareness.

Indexed as

NeoplasmsFemaleHumansMaleTumor MicroenvironmentL4-L5 fracturelocus minorislocus minoris resistentiaemalignancymetastasisovarian carcinomaprostate carcinomaserous carcinoma of the ovary

Identifiers

PMID33629603
PMCPMC7926049
OpenAlexW3129328005

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.