Trial reportBJOG : an international journal of obstetrics and gynaecology2021
Association of haemoglobin levels in the first trimester and at 26-30 weeks with fetal and neonatal outcomes: a secondary analysis of the Global Network for Women's and Children's Health's ASPIRIN Trial.
Trial report in BJOG : an international journal of obstetrics and gynaecology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05590260 (Prevention of Iron Deficiency Anemia Post-delivery), which is not on this map. Cited by 13 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevention of Iron Deficiency Anemia Post-delivery (PRIORITY Trial): A Randomized Controlled Trial of the Global Network for Women's and Children's Health Research
Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- The Effect of Maternal Haemoglobinopathies and Iron Deficiency Anaemia on Foetal Growth Restriction: A Systematic Review and Meta-Analysis.Maternal & child nutrition · 2025Pooled it
- Daily oral iron supplementation during pregnancy.The Cochrane database of systematic reviews · 2024Pooled it
- Maternal low and high hemoglobin concentrations and associations with adverse maternal and infant health outcomes: an updated global systematic review and meta-analysis.BMC pregnancy and childbirth · 2023Pooled it
- The impact of low-dose aspirin on hemoglobin levels in pregnancy: A secondary analysis of a randomized controlled trial for prevention of hypertensive disorders of pregnancy.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Trial
- Hemoglobin During Pregnancy Does Not Mediate the Relationship between Nutrition Supplements and Intrauterine Growth: A Secondary Data Analysis of Women First Preconception Nutrition Trial.The Journal of nutrition · 2025Trial
- Anemia and adverse outcomes in pregnancy: subgroup analysis of the CLIP cluster-randomized trial in India.BMC pregnancy and childbirth · 2022Trial
- Article
- Maternal Haemoglobin and Haematocrit During Pregnancy and Stillbirth Risk: A Prospective, Population-Based Birth Cohort Study.Paediatric and perinatal epidemiology · 2026Article
- Impact of low-dose aspirin on maternal haemoglobin levels during pregnancy: a protocol for a systematic review and meta-analysis.Systematic reviews · 2026Article
- Low-dose aspirin and anaemia risk in pregnancy: A scoping review with emphasis on low- and middle-income contexts.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2026Article
- Association Between Hypochromic Microcytic Anemia in Pregnancy and Cord Blood Levels of Cadmium, Lead, Manganese, Mercury, and Selenium.Biological trace element research · 2026Article
- Cohort profile: the Maharashtra Anaemia Study 3 (MAS 3)-a maternal-child cohort study up to age 18 years in India.BMJ open · 2025Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors at 17 institutions in 7 countries.
Funding
Abstract
objectiveLimited data are available from low- and middle-income countries (LMICs) on the relationship of haemoglobin levels to adverse outcomes at different times during pregnancy. We evaluated the association of haemoglobin levels in nulliparous women at two times in pregnancy with pregnancy outcomes.
designASPIRIN Trial data were used to study the association between haemoglobin levels measured at 6
settingObstetric care facilities in Pakistan, India, Kenya, Zambia, The Democratic Republic of the Congo and Guatemala. POPULATION: A total of 11 976 pregnant women.
methodsGeneralised linear models were used to obtain adjusted relative risks and 95% CI for adverse outcomes.
main outcome measuresPreterm birth, stillbirth, neonatal death, small for gestational age (SGA) and birthweight <2500 g.
resultsThe mean haemoglobin levels at 6
conclusionsBoth lower and some higher haemoglobin concentrations are associated with adverse fetal and neonatal outcomes at 6 TWEETABLE ABSTRACT: Both lower and some higher haemoglobin concentrations were associated with adverse fetal and neonatal outcomes at 6-13 weeks and 26-30 weeks of gestation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.