Evidence map›Paper›PMID 33629194›Full record

Trial reportJournal of cancer research and clinical oncology2021

Efficacy and safety of transbronchial microwave ablation therapy under moderate sedation in malignant central airway obstruction patients with respiratory failure: a single-institution retrospective study.

Kosuke Kashiwabara, Shinji Fujii, Shinsuke Tsumura, Kazuhiko Sakamoto, Hiroshi Semba

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Journal of cancer research and clinical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Interventional bronchoscopy in lung cancer treatment.Breathe (Sheffield, England) · 2024
    Review
  4. Review
  5. Overview of malignant central airway obstruction.Mediastinum (Hong Kong, China) · 2023
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kosuke KashiwabaraDepartment of Respiratory Medicine, Kumamoto Regional Medical Center, 5-16-10, Honjo, Kumamoto, 860-0811, Japan. kskkswbr@krmc.or.jp.ORCID http://orcid.org/0000-0001-6115-1193
Shinji FujiiDepartment of Respiratory Medicine, Kumamoto Regional Medical Center, 5-16-10, Honjo, Kumamoto, 860-0811, Japan.
Shinsuke TsumuraDepartment of Respiratory Medicine, Kumamoto Regional Medical Center, 5-16-10, Honjo, Kumamoto, 860-0811, Japan.
Kazuhiko SakamotoDepartment of Respiratory Medicine, Kumamoto Regional Medical Center, 5-16-10, Honjo, Kumamoto, 860-0811, Japan.
Hiroshi SembaDepartment of Respiratory Medicine, Kumamoto Regional Medical Center, 5-16-10, Honjo, Kumamoto, 860-0811, Japan.
Kumamoto Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe safety and efficacy of transbronchial microwave ablation (TMA) therapy in patients with malignant central airway obstruction (CAO) with respiratory failure remains unclear.

methodsA total of 38 patients with advanced non-small cell lung cancer (NSCLC) or lung metastases with malignant endoluminal obstruction received TMA therapy under moderate sedation and high fractions of inspired oxygen (FiO

resultsBoth the RF group and non-RF group received a median of two sessions of TMA. There was no significant difference in the percentage of patients who showed restored airway patency after the first session of TMA (90% vs. 96%), in the complication rate of TMA therapy (10% vs. 11%), or in the OS (7.1 months vs. 9.1 months) between the RF group and the non-RF group. Multivariate analysis identified no significant association between TMA therapy and the risk of death in malignant CAO patients with respiratory failure (p = 0.196).

conclusionTMA therapy under moderate sedation was well tolerated and effective in patients with malignant CAO, including those with respiratory failure.

Indexed as

AgedAged, 80 and overAirway ObstructionBronchoscopyCarcinoma, Non-Small-Cell LungFemaleFollow-Up StudiesHumansLung NeoplasmsMaleMicrowavesMiddle AgedProcedural SedationRadiofrequency AblationRespiratory InsufficiencyRetrospective StudiesEndoluminal tumor obstructionMicrowave ablationModerate sedationPost-anticancer therapyRespiratory failure

Identifiers

PMID33629194
PMCPMC11801845
OpenAlexW3133284680

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.