Evidence map›Paper›PMID 33628948›Full record

ArticleBMJ open ophthalmology2021

Exacerbation of visual hallucinations in Charles Bonnet syndrome due to the social implications of COVID-19.

Lee Jones, Lara Ditzel-Finn, Judith Potts, Mariya Moosajee

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05069753 (Patient Reported Visual Function Outcome Following Bilateral Cataract Surgery), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05069753 naunknown statusnot on this map

Patient Reported Visual Function Outcome Following Bilateral Cataract Surgery

TypeinterventionalSponsorRigshospitalet, DenmarkRan2021 to 2022Enrolled300ConditionsBilateral Cataract, Charles Bonnet SyndromeArmsImmediate sequential bilateral cataract surgery (ISBCS), Delayed sequential bilateral cataract surgery (DSBCS)
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

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  6. Archives of disease in childhood · 2025
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  9. Complex Hallucinations in Hospitalized Rehabilitation Patients With COVID-19.Archives of rehabilitation research and clinical translation · 2022
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lee JonesMoorfields Eye Hospital NHS Foundation Trust, London, UK.ORCID 0000-0002-8030-1211
Lara Ditzel-FinnGreat Ormond Street Hospital for Children, London, UK.
Judith PottsEsme's Umbrella, London, UK.
Mariya MoosajeeMoorfields Eye Hospital NHS Foundation Trust, London, UK.ORCID 0000-0003-1688-5360
Moorfields Eye Hospital NHS Foundation Trust · GBGreat Ormond Street Hospital · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectiveCharles Bonnet syndrome (CBS) occurs secondary to sight loss, characterised by spontaneous visual hallucinations. Symptom manifestation can be influenced by social isolation. This research aims to evaluate the effect of the COVID-19 pandemic lockdown on patients with CBS. METHODS AND ANALYSIS: A prospective cross-sectional survey of 45 individuals with active CBS. Open and closed ended questions were used to measure patient-reported features of hallucinatory experiences during the COVID-19 lockdown and perceived episode triggers. Analysis comprised of descriptive statistics, analysis of variance and associations, supplemented with qualitative descriptions.

resultsThe survey was operational for 31 days during the COVID-19 pandemic (June-July 2020). The mean (±SD) age of respondents was 69.3 (±18) years and the majority (42.2%) had macular disease. Loneliness during the lockdown was associated with changes in the nature of visual hallucinations (p=0.04). Individuals experiencing greater loneliness were, on average, older than those with no changes to their feelings of loneliness (mean age 73.3±17 vs 60.2±19 years; p=0.03). Despite experiencing greater feelings of loneliness (67%), most individuals (60%) had not accessed support services for this reason.

conclusionsAround half of respondents in this survey experienced exacerbation of visual hallucinations during the COVID-19 pandemic, which may partly be explained by loneliness and/or environmental triggers. We provide suggestions to promote effective patient self-management of symptoms.

Indexed as

COVID-19

Identifiers

PMID33628948
PMCPMC7880118
OpenAlexW3131806650

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.