Evidence map›Paper›PMID 33628831›Full record

ArticleBioMed research international2021

Long Noncoding RNA OIP5-AS1 Promotes the Disease Progression in Nasopharyngeal Carcinoma by Targeting miR-203.

Jian Tang, Chengxiao Fu, Yanwen Li, Shuangqin Chen, Xiaoxin Jiang, Wenqian Xu, Haitao Xie

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. The role of lncRNA OIP5-AS1 in cancer development and progression.Apoptosis : an international journal on programmed cell death · 2022
    Review
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jian TangDepartment of Infectious Disease, The First Affiliated Hospital, University of South China, Hengyang 421001, China.ORCID https://orcid.org/0000-0002-2180-0977
Chengxiao FuDepartment of Pharmacy, The First Affiliated Hospital, University of South China, Hengyang 421001, China.ORCID https://orcid.org/0000-0002-5435-5312
Yanwen LiDepartment of Laboratory Medicine, The First Affiliated Hospital, University of South China, Hengyang 421001, China.ORCID https://orcid.org/0000-0001-8773-0038
Shuangqin ChenDepartment of Neurology, The First Affiliated Hospital, University of South China, Hengyang 421001, China.ORCID https://orcid.org/0000-0001-8092-2125
Xiaoxin JiangDepartment of Laboratory Medicine, The First Affiliated Hospital, University of South China, Hengyang 421001, China.ORCID https://orcid.org/0000-0002-5990-6064
Wenqian XuDepartment of Laboratory Medicine, The First Affiliated Hospital, University of South China, Hengyang 421001, China.ORCID https://orcid.org/0000-0003-4962-3295
Haitao XieDepartment of Laboratory Medicine, The First Affiliated Hospital, University of South China, Hengyang 421001, China.ORCID https://orcid.org/0000-0001-9810-303X
First Affiliated Hospital of University of South China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasopharyngeal carcinoma (NPC) is a kind of malignancy generated from the nasopharyngeal epithelium. Recently, long noncoding RNA (lncRNA) has been shown to be involved in the regulation of many signaling pathways and is closely associated with carcinogenesis and tumor progression. However, the precise role of lncRNA Opa-interacting protein 5 antisense RNA 1 (OIP5-AS1) in NPC is not well understood. Here, we find that OIP5-AS1 is overexpressed in NPC patient specimens and NPC cell lines. Further investigations reveal that knockdown of OIP5-AS1 significantly inhibits the proliferation, migration, and invasion and accelerates the apoptosis of NPC cells

Indexed as

Gene Expression Regulation, NeoplasticAnimalsHumansMaleMiceMice, Inbred BALB CMice, NudeMicroRNAsNasopharyngeal CarcinomaNasopharyngeal NeoplasmsRNA, Long NoncodingRNA, Neoplasmlong noncoding RNA OIP5, humanMicroRNAsMIRN203 microRNA, humanRNA, Long NoncodingRNA, Neoplasm

Identifiers

PMID33628831
PMCPMC7884132
OpenAlexW3128361767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.