ArticleBioMed research international2021
Neutrophil-Lymphocyte Ratio as an Initial Screening Biomarker for Differential Diagnosis of Cushing's Syndrome from Nonfunctional Adenoma in Patients with an Adrenal Mass.
Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Cardiometabolic and inflammatory profiles associated with intermediate post-DST cortisol levels (1.0-1.8 µg/dL) in patients with adrenal incidentalomas.BMC endocrine disorders · 2026Article
- Leukocytosis in Cushing's syndrome persists post-surgical remission and could predict a lower remission prognosis in patients with Cushing's disease.Journal of endocrinological investigation · 2025Article
- (Un)Tying the Knot: Oxidative Stress, Inflammatory Markers, and Lipid Status in Dogs with Hypercortisolism.Animals : an open access journal from MDPI · 2024Article
- A novel model using leukocytes to differentiating mild autonomous cortisol secretion and non-functioning adrenal adenoma.Scientific reports · 2024Article
- [Comparison of coagulation function between adrenocorticotropic hormone independent Cushing syndrome and nonfunctional adrenal adenoma and its influence factors].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023Article
- Increasing of Cortisol Level and Neutrophil-Lymphocyte-Ratio are Associated with Severity Level and Sleep Disturbances in Acute Ischemic Stroke.International journal of general medicine · 2023Article
- The Role of Serum Inflammation-Based Scores in Diagnosis and Assessing Remission in Cushing's Disease.Sisli Etfal Hastanesi tip bulteni · 2023Article
- Inflammatory biomarkers in the evaluation of pediatric endogenous Cushing syndrome.European journal of endocrinology · 2022Article
- Neutrophil-to-Lymphocyte, Platelet-to-Lymphocyte Ratios, and Systemic Immune-Inflammation Index as Potential Biomarkers of Chronic Inflammation in Patients with Newly Diagnosed Acromegaly: A Single-Centre Study.Journal of clinical medicine · 2021Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAssessing excess adrenal hormones is important in patients with adrenal mass. Current screening tests for excess cortisol hormones are complex, so it cannot be done sometimes due to the limited medical resources. The aim of the study was to evaluate whether the neutrophil-lymphocyte ratio (NLR) can be used as an initial screening biomarker for Cushing's syndrome (CS) in patients with an adrenal mass.
methodsThis retrospective study included a total of 185 patients with CS and 185 patients with nonfunctional adrenal adenoma (matched 1 : 1 by sex, body mass index, and discharge date). The NLR was compared between the two groups. The association between NLR and serum and urinary cortisol concentrations was analyzed, and an NLR cut-off value for CS screening was calculated.
resultsNLR (3.38 (2.33, 5.45) vs. 2.13 (1.74, 3.00),
conclusionThe NLR may be useful for initial screening for CS among patients with an adrenal mass as an easy and convenient marker.
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