Evidence map›Paper›PMID 33628726›Full record

ArticleFrontiers in oncology2020

CTHRC1 Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Kidney Renal Papillary Cell Carcinoma and Kidney Renal Clear Cell Carcinoma.

Fenfang Zhou, Dexin Shen, Yaoyi Xiong, Songtao Cheng, Huimin Xu, Gang Wang, Kaiyu Qian, Lingao Ju, Xinhua Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

  1. Potential role of CTHRC1 in renal fibrosis.Molecular biology reports · 2026
    Review
  2. The Zinc Finger Ran-Binding Protein 3 (ZRANB3): An Advanced Perspective.International journal of molecular sciences · 2026
    Review
  3. CTHRC1Frontiers in immunology · 2026
    Article
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  16. The expression and methylation ofFrontiers in genetics · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Fenfang ZhouDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Dexin ShenDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Yaoyi XiongDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Songtao ChengDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Huimin XuDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Gang WangDepartment of Biological Repositories, Zhongnan Hospital of Wuhan University, Wuhan, China.
Kaiyu QianDepartment of Biological Repositories, Zhongnan Hospital of Wuhan University, Wuhan, China.
Lingao JuDepartment of Biological Repositories, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xinhua ZhangDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Wuhan University · CNZhongnan Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney renal clear cell carcinoma (KIRC) and kidney renal papillary cell carcinoma (KIRP) are the most common RCC types. RCC has high immune infiltration levels, and immunotherapy is currently one of the most promising treatments for RCC. Collagen triple helix repeat containing 1 (CTHRC1) is an extracellular matrix protein that regulates tumor invasion and modulates the tumor microenvironment. However, the association of

Indexed as

collagen triple helix repeat containing 1 (CTHRC1)immune infiltrationkidney renal clear cell carcinomakidney renal papillary cell carcinomaprognosis

Identifiers

PMID33628726
PMCPMC7898899
OpenAlexW3126977391

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.