Evidence map›Paper›PMID 33628539›Full record

ArticleCase reports in hematology2021

Diagnostic Challenges of Anaplastic Large Cell Lymphoma in a Resource-Limited Setting: A Case Report and Literature Review.

Oluomachi Charity Nnachi, Innocent Paul Ezenwenyi, Augustine Ejike Okoye, Chinedu Obasi Akpa, Chukwuma Joseph Uzoigwe, Gabriel Chima Ugwu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in hematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Oluomachi Charity NnachiDepartment of Haematology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi, Nigeria.ORCID https://orcid.org/0000-0002-9393-3920
Innocent Paul EzenwenyiDepartment of Haematology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi, Nigeria.ORCID https://orcid.org/0000-0002-6164-5633
Augustine Ejike OkoyeDepartment of Haematology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi, Nigeria.ORCID https://orcid.org/0000-0001-9350-5160
Chinedu Obasi AkpaDepartment of Haematology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi, Nigeria.ORCID https://orcid.org/0000-0002-6407-4901
Chukwuma Joseph UzoigweDepartment of Histopathology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi, Nigeria.ORCID https://orcid.org/0000-0002-0648-3723
Gabriel Chima UgwuDepartment of Haematology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi, Nigeria.ORCID https://orcid.org/0000-0001-6682-1096
Federal Teaching Hospital Abakaliki · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anaplastic large cell lymphoma (ALCL) is a rare variety of non-Hodgkin's lymphoma with diverse morphologic variants. Due to the similarity of the different variants with other lymphoma entities, misdiagnosis may be inevitable when immunohistochemical and cytogenetic techniques are not available and histology alone is employed. We report a case of a 43-year-old woman with a seven-month history of neck swelling which was complicated by ulceration of the mass and pathological fracture of the right clavicle after two months delay in arriving at a correct diagnosis. Several attempts to arrive at definitive diagnosis using histology alone gave divergent reports which all misdiagnosed the case until it was sent to a facility outside the country. Our report highlights the limitations and challenges of histology in making a definitive diagnosis of ALCL and the overt importance of immunohistochemical and cytogenetic techniques which are largely unavailable in resource-constrained environment typical of tertiary centers in Nigeria and most sub-Saharan Africa countries.

Identifiers

PMID33628539
PMCPMC7892240
OpenAlexW3129760855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.