Evidence map›Paper›PMID 33628508›Full record

ReviewMultiple sclerosis international2021

Family Planning for People with Multiple Sclerosis in Saudi Arabia: an Expert Consensus.

Mohammed Al Jumah, Yaser Al Malik, Nuha M AlKhawajah, Jameelah Saeedi, Ibtisam AlThubaiti, Saeed Bohlega, Reem F Bunyan, Edward J Cupler, Ahmed ElBoghdady, Ahmed Hassan and 2 more

Open access · hybridAbstract readReview
In one paragraph

Review in Multiple sclerosis international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 2 countries.

Mohammed Al JumahNeurology Department, King Fahad Medical City, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-9820-9579
Yaser Al MalikCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Nuha M AlKhawajahCollege of Medicine, King Saud University, Riyadh, Saudi Arabia.
Jameelah SaeediNeurology Department, King Abdullah Bin Abdulaziz University Hospital, Riyadh, Saudi Arabia.
Ibtisam AlThubaitiNeurology Department, King Fahad Military Medical Complex Dhahran, Dammam Eastern Region, Saudi Arabia.
Saeed BohlegaDepartment of Neurosciences, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Reem F BunyanNeurology Department, King Fahad Specialist Hospital Dammam, Dammam Eastern Region, Saudi Arabia.
Edward J CuplerDepartment of Neurosciences, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.
Ahmed ElBoghdadyMerck KGaA, Riyadh, Saudi Arabia.
Ahmed HassanDepartment of Neurosciences, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.
Eman Nassim AliNeurology Department, King Fahad Specialist Hospital Dammam, Dammam Eastern Region, Saudi Arabia.
Marinella ClericoClinical and Biological Sciences Department, University of Torino, Orbassano, Italy.
King Faisal Specialist Hospital & Research Centre · SAKing Fahad Specialist Hospital · SAKing Abdulaziz Hospital · SAKing Fahd Medical City · SAKing Fahd Military Medical Complex · SAKing Saud bin Abdulaziz University for Health Sciences · SAKing Saud Medical City · SAUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

More than half of all patients with multiple sclerosis (MS) in the Kingdom of Saudi Arabia (KSA) are women of childbearing age. Raising a family is an important life goal for women in our region of the world. However, fears and misconceptions about the clinical course of relapsing-remitting MS (RRMS) and the effects of disease-modifying drugs (DMDs) on the foetus have led many women to reduce their expectations of raising a family, sometimes even to the point of avoiding pregnancy altogether. The increase in the number of DMDs available to manage RRMS and recent studies on their effects in pregnancy have broadened management options for these women. Interferon beta now has an indication in Europe for use during pregnancy (according to clinical need) and can be used during breastfeeding. Glatiramer acetate is a further possible option for women with lower levels of RRMS disease activity who are, or about to become, pregnant; natalizumab may be used up to 30 weeks in patients with higher levels of disease activity. Where possible, physicians need to support and encourage women to pursue their dream of a fulfilling family life, supported where necessary by active interventions for RRMS that are increasingly evidence based.

Identifiers

PMID33628508
PMCPMC7899766
OpenAlexW3130990174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.