Evidence map›Paper›PMID 33628504›Full record

ArticleRadiology research and practice2021

Predicting Molecular Subtypes of Breast Cancer with Mammography and Ultrasound Findings: Introduction of Sono-Mammometry Score.

Sana Shaikh, Afshan Rasheed

Registry-linked trialAbstract read
In one paragraph

Article in Radiology research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07354490 (Imaging-Pathologic Correlation of Breast Cancer), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07354490 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Imaging-Pathologic Correlation of Breast Cancer: Mammographic and Sonographic Features in Relation to Molecular Classification

TypeobservationalSponsorAssiut UniversityRan2026 to 2028Enrolled122ConditionsBreast CancerArmsDiagnostic test: Ultrasound and Mammogram
3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sana ShaikhRadiology Department, Sindh Institute of Urology and Transplantation (SIUT), Karachi 74100, Pakistan.ORCID https://orcid.org/0000-0003-0240-7667
Afshan RasheedOncology Department, Sindh Institute of Urology and Transplantation (SIUT), M. A. Jinnah Road, Karachi 74100, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the correlation of sonographic and digital mammographic features with molecular classification of breast cancer. Imaging features from 313 patients with preliminary ultrasound and digital mammogram between November 2017 and May 2020 were compared with histopathology and immunohistochemical analysis for the prediction of molecular classification of breast cancer. We also devised a score called "sono-mammometry" score consisting of few simple imaging features which can easily be performed in outpatient settings. We studied that non-triple-negative breast cancers are predominantly hypoechoic and strongly correlate with the presence of irregular spiculated margins along with peripheral echogenic halo, posterior shadowing, and microcalcifications, while there is considerable variation in imaging features of TNBC as some of its imaging features overlap with those of typical benign tumors. Although imaging characteristics are helpful in the prediction of molecular classification, the prognostication value of these imaging features is still weak. There is considerable variation in imaging features which warrants vigilance towards improved diagnostic performance. To help better understand these features, our sono-mammometry score can serve as straightforward test which is assumed to be functional and productive in resource-limited settings.

Identifiers

PMID33628504
PMCPMC7886512

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.