Evidence map›Paper›PMID 33628374›Full record

ArticleOxidative medicine and cellular longevity2021

Levels of Cyclooxygenase 2, Interleukin-6, and Tumour Necrosis Factor-

Asma Shaikh-Kader, Nicolette N Houreld, Naresh K Rajendran, Heidi Abrahamse

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Management strategies for burning mouth syndrome: a comprehensive review.Journal of oral & facial pain and headache · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Silver Nanoparticles Prepared UsingJournal of fungi (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Article
  11. Photobiomodulation studies on diabetic wound healing: An insight into the inflammatory pathway in diabetic wound healing.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Asma Shaikh-KaderLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, Johannesburg 2028, South Africa.ORCID https://orcid.org/0000-0002-4396-4788
Nicolette N HoureldLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, Johannesburg 2028, South Africa.ORCID https://orcid.org/0000-0002-1515-8260
Naresh K RajendranLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, Johannesburg 2028, South Africa.ORCID https://orcid.org/0000-0003-4401-6912
Heidi AbrahamseLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, Johannesburg 2028, South Africa.ORCID https://orcid.org/0000-0001-5002-827X
University of Johannesburg · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemicals and signaling molecules released by injured cells at the beginning of wound healing prompt inflammation. In diabetes, prolonged inflammation is one of the probable causes for delayed wound healing. Increased levels of cyclooxygenase-2 (cox-2), interleukin-6 (IL-6), and tumour necrosis factor-alpha (TNF-

Indexed as

Low-Level Light TherapyCell Culture TechniquesCell ShapeCell SurvivalCyclooxygenase 2FibroblastsHumansInterleukin-6Tumor Necrosis Factor-alphaCyclooxygenase 2Interleukin-6Tumor Necrosis Factor-alpha

Identifiers

PMID33628374
PMCPMC7896847
OpenAlexW3132215112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.