Evidence map›Paper›PMID 33628340›Full record

ArticleDisease markers2021

Serum Levels of BDNF in Patients with Adenoma and Colorectal Cancer.

Zhe Wang, Shuang Wang, Yu Liu, Shan Gao, Yunqing Yu, Zhaolan Hu

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Tumor Innervation: From Bystander to Emerging Therapeutic Target for Cancer.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhe WangDepartment of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0003-1335-7802
Shuang WangMedical Research Center and Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, China.
Yu LiuDepartment of Anatomy and Neurobiology, School of Basic Medical Science, Central South University, Changsha, China.
Shan GaoDepartment of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Yunqing YuDepartment of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Zhaolan HuDepartment of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0003-1535-914X
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study is aimed at examining the serum levels of brain-derived neurotrophic factor (BDNF) and investigating its role in differential diagnosis of colorectal cancer (CRC).

Indexed as

AdenomaAgedArea Under CurveBiomarkers, TumorBrain-Derived Neurotrophic FactorCarcinoembryonic AntigenCase-Control StudiesColorectal NeoplasmsEarly Detection of CancerFemaleHumansMaleMiddle AgedNeoplasm StagingTumor BurdenBDNF protein, humanBiomarkers, TumorBrain-Derived Neurotrophic FactorCarcinoembryonic Antigen

Identifiers

PMID33628340
PMCPMC7895608
OpenAlexW3130639341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.