Evidence map›Paper›PMID 33628317›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Evaluation of

Zemene Demelash Kifle, Birhanu Berihun Kidanu, Tesfaye Yimer Tadesse, Teshome Fentik Belachew, Seyfe Asrade Atnafie

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Journal of tropical medicine · 2024
    Article
  4. Article
  5. Metabolism open · 2021
    Article
  6. Methanolic Crude Extract ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  7. BioMed research international · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zemene Demelash KifleUniversity of Gondar, College of Medicine and Health Sciences, School of Pharmacy, Department of Pharmacology, Gondar, Ethiopia.ORCID https://orcid.org/0000-0001-7030-2782
Birhanu Berihun KidanuUniversity of Gondar, College of Veterinary Medicine and Animal Sciences, Department of Veterinary Pharmacy, Gondar, Ethiopia.
Tesfaye Yimer TadesseDebretabor University, College of Health Science, Department of Pharmacy, Debre Tabor, Ethiopia.
Teshome Fentik BelachewDepartment of Pharmacy, Debre Birhan Health Science College, Debre Birhan, Ethiopia.
Seyfe Asrade AtnafieUniversity of Gondar, College of Medicine and Health Sciences, School of Pharmacy, Department of Pharmacology, Gondar, Ethiopia.ORCID https://orcid.org/0000-0002-8262-0590
University of Gondar · ETDebre Berhan University · ETDebre Tabor University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEthiopia has several medicinal plants that have been used for their antidiarrheal activity.

methodsAntidiarrheal activity of extract fractions obtained from different solvents was evaluated by using small intestine transit, enteropooling, and castor oil-induced diarrhea animal models. In all animal models, the solvent fractions treated groups were treated with three different doses (100 mg/kg, 200 mg/kg, and 400 mg/kg) of the solvent fractions, while the negative control group was treated with a vehicle (distilled water), and positive control group was treated with loperamide.

resultsThe acute toxicity test revealed that the LD

conclusionThe extract fractions obtained from different solvents have shown significant antidiarrheal activity. Thus, this finding supports the claimed traditional use of

Identifiers

PMID33628317
PMCPMC7896859
OpenAlexW3133250513

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.