Evidence map›Paper›PMID 33628307›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2021

Antidiabetic Activity of Widely Used Medicinal Plants in the Sri Lankan Traditional Healthcare System: New Insight to Medicinal Flora in Sri Lanka.

Keddagoda Gamage Piyumi Wasana, Anoja Priyadarshani Attanayake, Kamani Ayoma Perera Wijewardana Jayatilaka, Thilak Priyantha Weerarathna

Open access · hybridAbstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Food science & nutrition · 2024
    Review
  4. Review
  5. Article
  6. Metabolism open · 2022
    Article
  7. Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2022
    Review
  8. Article
  9. Antidiabetic Activity of Hydromethanolic Extract of CrudeJournal of experimental pharmacology · 2022
    Article
  10. Synergistic Anti-inflammatory and Neuroprotective Effects ofFrontiers in cell and developmental biology · 2021
    Article
  11. Phytochemicals Characterization and Antidiabetic Efficacy ofIranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Keddagoda Gamage Piyumi WasanaDepartment of Biochemistry, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.ORCID https://orcid.org/0000-0002-5003-4490
Anoja Priyadarshani AttanayakeDepartment of Biochemistry, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.ORCID https://orcid.org/0000-0002-4365-7956
Kamani Ayoma Perera Wijewardana JayatilakaDepartment of Biochemistry, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.ORCID https://orcid.org/0000-0002-6714-0273
Thilak Priyantha WeerarathnaDepartment of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.ORCID https://orcid.org/0000-0003-0047-6669
University of Ruhuna · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of medicinal plant extracts and their isolated bioactive compounds for the management of diabetes mellitus has been tremendously increased in recent decades. The present study aimed at providing in-depth information on medicinal flora that has been widely used in the Sri Lankan traditional healthcare system for the management of diabetes mellitus. The data of this review article were obtained from published articles from January 2000 to September 2020 in scientific databases of PubMed, Web of Science, and Google Scholar. In this review, a total number of 18 medicinal plants with the antidiabetic activity were expressed, and their isolated antidiabetic active compounds were highlighted as new drug leads. Results of the reported studies revealed that medicinal plants exert a potent antidiabetic activity via both in vitro and in vivo study settings. However, bioactive compounds and antidiabetic mechanism (s) of action of many of the reported medicinal plants have not been isolated/elucidated the structure in detail, to date. Reported antidiabetic medicinal plants with other properties such as antioxidant and antihyperlipidemic activities deliver new entities for the development of antidiabetic agents with multiple therapeutic targets. This is a comprehensive review on potential antidiabetic activities of the Sri Lankan medicinal plants that have been widely used in the traditional healthcare system. The information presented here would fill the gap between the use of them by traditional healers in the traditional medicine healthcare system in Sri Lanka and their potency for development of new drug entities in future.

Identifiers

PMID33628307
PMCPMC7886531
OpenAlexW3127428255

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.