Evidence map›Paper›PMID 33628232›Full record

ReviewAnesthesiology research and practice2021

Perioperative Intravenous Patient-Controlled Analgesic Efficacy of Morphine with Combined Nefopam and Parecoxib versus Parecoxib in Gynecologic Surgery: A Randomized, Double-Blind Study.

Varinee Lekprasert, Lapuskorn Yapanan, Wichai Ittichaikulthol, Rungrawan Buachai, Phimol Soisod, Areepan Sophonsritsuk

Open access · goldAbstract readReview
In one paragraph

Review in Anesthesiology research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Varinee LekprasertDepartment of Anesthesiology, Faculty of Medicine Ramathidodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Lapuskorn YapananDepartment of Anesthesiology, Faculty of Medicine Ramathidodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Wichai IttichaikultholDepartment of Anesthesiology, Faculty of Medicine Ramathidodi Hospital, Mahidol University, Bangkok 10400, Thailand.ORCID https://orcid.org/0000-0002-8288-3876
Rungrawan BuachaiDepartment of Anesthesiology, Faculty of Medicine Ramathidodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Phimol SoisodDepartment of Anesthesiology, Faculty of Medicine Ramathidodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Areepan SophonsritsukReproductive Endocrinology and Infertility Unit, Department of Obstetrics and Gynaecology, Faculty of Medicine Ramathidodi Hospital, Mahidol University, Bangkok 10400, Thailand.ORCID https://orcid.org/0000-0002-4589-0030
Mahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNefopam is a non-NSAIDs and opioid sparing centrally acting drug which is effective for a multimodal postoperative analgesia. The present study aimed to evaluate the analgesic efficacy of nefopam combined with parecoxib for gynecologic surgery.

methodsThis randomized double-blinded control trial recruited participants (

resultsMorphine consumption within 24 hours and adverse effects were not significantly different between both groups. Mean difference and 95% confident interval of morphine consumption between both groups was 1.00 (-4.56, 4.76),

conclusionsThe combined administration of nefopam and parecoxib during gynecologic surgery slightly reduced the VNRS at 6 and 12 hours postoperatively more than treatment with parecoxib.

Identifiers

PMID33628232
PMCPMC7895606
OpenAlexW3129533515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.